β-diketone-cobalt complexes, a family of newly synthesized non-platinum metal compounds, exhibit potential antitumor activity; however, the antitumor mechanism is unclear. The current study investigated the mechanism by which β-diketone-cobalt complexes inhibit rat C6 glioma cell proliferation. It was found that β-diketone-cobalt complexes suppress rat C6 glioma cell viability in a dose-depende...

Phage-displayed peptides that selectively bind to aldolase catalytic antibody 93F3 when bound to a particular 1,3-diketone hapten derivative have been developed using designed selection strategies with libraries containing 7-12 randomized amino acid residues. These phage-displayed peptides discriminated the particular 93F3-diketone complex from ligand-free 93F3 and from 93F3 bound to other 1,3-...

The title compound, C(15)H(11)BrO(2), exists as a diketone in which the two benzoyl groups are nearly perpendicular to each other [dihedral angles = 79.9 (1) and 87.4 (1)° in the two independent mol-ecules].

The glaucous appearance of wheat (Triticum aestivum) and barley (Hordeum vulgare) plants, that is the light bluish-gray look of flag leaf, stem, and spike surfaces, results from deposition of cuticular β-diketone wax on their surfaces; this phenotype is associated with high yield, especially under drought conditions. Despite extensive genetic and biochemical characterization, the molecular gene...

A novel naphthalimide derivative endowed with a diketone functionality has been synthesized and used to develop a family of highly symmetric, flat, n-type semiconducting naphthalimide-based pyrazinacenes. By changing the symmetry of these compounds and the number of naphthalimide constituents, fine tuning of their electrochemical, photophysical, and morphological properties is achieved.

The synthesis of modified diketone ligands and the preparation of soluble Er3þ and Eu3þ tris-(b-diketone)phenantroline complexes are described. The complexes, embedded in thin films of different conjugated and non-conjugated polymeric host matrices were studied by luminescence spectroscopy and used as active layers in organic light emitting single layer diodes to observe their characteristic em...

4-Fluoropyrazole systems may be prepared by a single, sequential telescoped two-step continuous gas/liquid-liquid/liquid flow process from diketone, fluorine gas and hydrazine starting materials.

Angelica gigas NAKAI is used to treat dysmenorrhea, amenorrhea, menopause, abdominal pain, injuries, migraine, and arthritis. The present study provided a physicochemical and toxicological characterization of compounds in A. gigas NAKAI (decursin, decursinol angelate, diketone decursin, ether decursin, epoxide decursin and oxim decursin). Diketone decursin (173.16 μg/mL) and epoxide decursin (1...

The formation of 1,3-diketones was observed in the reactions of bulky acyl chlorides with methyllithium. The reaction products depend on the steric hindrance around the carbonyl group of the acyl chloride and the electronic effect of the group(s) linked to the carbonyl. When the steric hindrance around the carbonyl group of the acyl chloride is big enough, the 1,3-diketone is the only product. ...