نتایج جستجو برای: disease rat
تعداد نتایج: 1740446 فیلتر نتایج به سال:
Background and Objective: Alzheimer’s disease (AD) is the most common neurodegenerative disease worldwide. At now Pharmacological treatments available only can slow down the progression of symptoms but can not treat the disease. It is established that benzodiazepines, and related agonists at the benzodiazepine site of GABA receptor, present anxiolytic and amnesic properties, whereas inverse ago...
Abstract Dust clouds are ubiquitous in the atmospheres of hot Jupiters and affect their observable properties. The alignment dust grains resulting polarization provide a promising way to study magnetic fields exoplanets. Moreover, grain size distribution plays an important role physical chemical processes atmospheres, which rather uncertain. In this paper, we first by radiative torques (RATs). ...
This study determined the hemodynamic effects of chronic ethanol in telemetered freely moving age-matched spontaneously hypertensive (SHR) and Wistar-Kyoto (WKY) rats. Changes in blood pressure (BP), heart rate (HR), and plasma norepinephrine (as index of sympathetic activity) were evaluated in pair-fed rats receiving liquid diet with or without ethanol (5%, w/v) for 12 weeks. The SHRs exhibite...
Antinociceptive action of diclofenac (non-opioid analgesic) was investigated in male and female normotensive (WKY) and genetically established hypertensive (SHR) and normotensive WAG. The drug was administered subcutaneously in doses of 10 mg/kg body weight and per os 20 mg/kg and 40 mg/kg. Statistically significant differences in pain threshold were reported between male and female rats of inv...
THE article by Kurtz and Morris 1 in this issue of Hypertension raises important issues with regard to the use of genetically hypertensive rats. These issues are 1) the origins of various stocks, 2) the definition and maintenance of the integrity of various stocks of interest in hypertension research, and 3) the construction, appropriateness, and use of control strains for comparison with hyper...
INTRODUCTION Traumatic renal artery thrombosis (RAT) is an uncommon disease especially secondary to blunt trauma. There are some reports about RAT but reports of RAT involving accessory renal arteries are rare. Therapy of RAT is often surgical management such as nephrectomy, arterial revascularization or conservative management. We report a 15-year-old girl with RAT and accessory renal artery s...
Background and Objectives: Alzheimer's disease is the most common form of dementia. KAT2B (Lysine Acetyltransferase 2B) is a mitochondrial protein known as mitochondria clearing control organ by mitophagy. PRDX6 (Peroxiredoxin 6) is a key regulator of mitophagy and plays a critical role in maintaining mitochondrial ROS (Reactive oxygen species) homeostasis. Therefore, the purpose of this study ...
In metabolic balance studies the intake and excretion of sodium, potassium, and water were measured in spontaneously hypertensive rats (SHRs) of the Okamoto-Aoki strain and age-matched Wistar Kyoto rats (WKYs) that were 3 through 13 weeks of age. While fed their usual chow, young SHRs exhibited differences in excretion as compared to WKYs consuming essentially equivalent amounts of food and wat...
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