نتایج جستجو برای: disease rat

تعداد نتایج: 1740446  

پایان نامه :وزارت بهداشت، درمان و آموزش پزشکی - دانشگاه علوم پزشکی و خدمات بهداشتی درمانی تهران 0

یکی از وسیعترین کاربردهای درمانی نمکهای لیتیم در بیماری مانیک -دپرسیو می باشد. شواهدی در دست است که نشان می دهد، لیتیم می تواند پاسخهای ایجاد شده توسط پیامبرهای ثانویه مسیر فسفواینوزیتاید را تحت تاثیر قرار دهد. از طرفی آمینوگلیکوزیدها نیز می توانند در کنار اثرات ضد میکروبی خود، در متابولیسم پلی فسفواینوزیتایدها تداخل نمایند. بدین تریب که از فعال شدن فسفولیپاز سلولی ممانعت نموده و تشکیل dag, ip3...

Journal: :Asian Journal of Pharmaceutical and Clinical Research 2023

Objective: The global pandemic of Coronavirus Disease 2019 (COVID-19) is still spreading. Because this, it urgently necessary to develop quick, easy, and accurate assays identify severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection. For the purpose diagnosing COVID-19 cases, quick SARS-CoV-2 antigen detection test’s performance attributes should be assessed contrasted with gol...

Akbar Hajizadeh Moghaddam , Hananeh Ahmadnia,

Hesperetin (Hst) is a well-known bioflavonoid, has low bioavailability. Hesperetin nanoparticles (Nano-Hst) enhance its bioavailability. Nano-Hst were not explored for their potential therapeutic activities in Alzheimer’s disease (AD). Hence, the present study was performed to evaluate the protective effect of Nano-Hst in comparison to free Hesperetin on against intracerebroventricular in...

حاتمی, حمیرا, رحیملوی مرجانی, زاهده, علی همتی, علی رضا,

  Background: Multiple sclerosis (MS ( is one of the chronic autoimmune diseases of the central nervous system with unknown etiology. Nitric oxide (NO) as a free radical has contradictory effect on the central nervous system and on MS disease. Nitric oxide is one of the distractive factors of the immune system and is a factor in the destruction of myelin. On the other hand, there is an interact...

Journal: :international journal of molecular and cellular medicine 0
amin ataie cellular and molecular biology research center, babol university of medical science, babol, iran.سازمان اصلی تایید شده: دانشگاه علوم پزشکی بابل (babol university of medical sciences) ramin ataee pharmacy faculty, mazandaran university of medical science, sari, iran.سازمان اصلی تایید شده: دانشگاه مازندران (mazandaran university) mohmmad shadifar pastor institute of iran, tehran, iran. sima shahabi cellular and molecular biology research center, babol university of medical science, babol, iran.سازمان اصلی تایید شده: دانشگاه علوم پزشکی بابل (babol university of medical sciences) seyed mohsen aghajanpour mir cellular and molecular biology research center, babol university of medical science, babol, iran.سازمان اصلی تایید شده: دانشگاه علوم پزشکی بابل (babol university of medical sciences) younes hosseinpour pastor institute of iran, tehran, iran.

it has been hypothesized that elevated plasma homocysteine (hcy) plays a role in the pathogenesis of alzheimer’s disease (ad) and age-related cognitive decline. the mechanism of hcy neurotoxicity in the brain is controversial as well hcy is a ligand of nmda receptor. memantine, an uncompetitive antagonist of n-methyl-d-aspartate (nmda) receptors approved for the treatment of moderate to severe ...

Journal: :Folia Neuropathologica 2023

AMA Wang Y, Wu X, Ren W, et al. Protective effects of fisetin in an Aβ1-42-induced rat model Alzheimer’s disease. Folia Neuropathologica. 2023. doi:10.5114/fn.2023.126893. APA Wang, Y., Wu, X., Ren, W., Liu, Dai, & S. (2023). https://doi.org/10.5114/fn.2023.126893 Chicago Yunting, Xueling Wujiang Yanxia Shuo and Qing Huo "Protective disease". Harvard S., Huo, Q., Sun, Y. MLA Yunting disease." N...

Background and Objectives: Alzheimer’s disease (AD) is a neurodegenerative disease accompanied by common emotional symptoms such as anxiety and fear. The aim of this study was investigating the anti-anxiety and antioxidant effects of sumac extract and its nano-phytosome, in streptozotocin (STZ)-induced rat model of Alzheimerchr('39')s disease Materials and Methods: In this experimental study, ...

Journal: :iranian journal of pharmaceutical research 0
jalal pourahmad - mehrdad faizi department of pharmacology and toxicology, faculty of pharmacy, shahid beheshti university of medical sciences, p.o. box 14155-6153, tehran, iran. enayatollah seydi department of pharmacology and toxicology, faculty of pharmacy, shahid beheshti university of medical sciences, p.o. box 14155-6153, tehran, iran. sadegh abarghuyi faculty of pharmacy, shahid beheshti university of medical sciences, p.o. box 14155-6153, tehran, iran. ahmad salimi department of pharmacology and toxicology, faculty of pharmacy, shahid beheshti university of medical sciences, p.o. box 14155-6153, tehran, iran. sanaz nasoohi department of pharmacology and toxicology, faculty of pharmacy, shahid beheshti university of medical sciences, p.o. box 14155-6153, tehran, iran.

alzheimer’s disease (ad) is a progressive neurodegenerative disorder that affects regions of the brain that control cognition, memory, language, speech and awareness to one’s physical surroundings. the pathological initiation and progression of ad is highly complex and its prevalence is on the rise. in his study, alzheimer's disease was induced with single injection of amyloid-β (aβ) pepti...

پایان نامه :وزارت علوم، تحقیقات و فناوری - دانشگاه محقق اردبیلی - دانشکده علوم 1389

در این مطالعه، اثرات سیستم کانابینوئیدی و سیستم گابائرژیک و نیز تداخل این دو سیستم در ناحیه قشر جلوی پیشانی رت ها در مدل رفتاری اضطراب (elevated plus-maze) ارزیابی گردید. تزریق یک طرفه دوزهای مختلف آگونیست اختصاصی گیرنده cb1 win55212-2,( µg/rat4 ،2، 5/0) در ناحیه قشر پیش پیشانی، درصد زمان ورود به بازوی باز ( (%oatو دفعات ورود به بازوی باز %oae)) را کاهش داد که نشان دهنده افزایش رفتار های شبه اض...

Journal: :British Journal of Surgery 2021

Abstract Renal Auto transplantation (RAT) is the surgical procedure in which kidney initially removed and subsequently re-implanted a different position, allowing for improved outcomes conditions involving ureteral pathology, renovascular neoplastic disease primarily. In this paper, we aim to build upon understanding of RAT especially its effectiveness treating patients with hypertension second...

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