Although apparently the first effective parathyroid extract was prepared by Moussu in 1898, some time elapsed before Hanson (1926) and Collip (1925) clearly demonstrated that an active extract of consistent potency could be prepared by using hot dilute hydrochloric acid. Since that time there have been a number of attempts to purify such extracts further. Some further purification was achieved ...

Ion-exchange displacement chromatography has been adapted to centrifugal partition chromatography. The use of an ionic liquid, benzalkonium chloride, as a strong anion-exchanger has proven to be efficient for the preparative separation of phenolic acid regioisomers. Multigram quantities of a mixture of three hydroxycinnamic acid isomers were separated using iodide as a displacer. The displaceme...

In Part 1 of this series of papers (Partridge & Westall, 1949) it was shown that, whilst the baseexchange resin Zeo Karb 215 may be used with success for the separation of the neutral and acidic amino-acids, certain difficulties arise when the separation of basic substances is attempted. These difficulties were traced to the phenolic hydroxyl groups of the resin. Resins of the sulphonated pheno...