Tidal disruption events are an excellent probe for supermassive black holes in distant inactive galaxies because they show bright multi-wavelength flares lasting several months to years. AT2019dsg presents the first potential association with neutrino emission from such explosive event.

The optimal locating of facilities has large effects on economic benefits, providing satisfactory service and levels of customer satisfaction. One of the new topics discussed in location problems is hub location and hub facilities are subject to unpredictable disruptions. This paper proposes a nonlinear integer model for reliable single allocation hub location problem that considers backup hub,...

BACKGROUND AND PURPOSE Surface disruption, either ulceration or fibrous cap rupture, has been identified as a key feature of the unstable atherosclerotic plaque. In this prospective observational study, we sought to determine the characteristics of the carotid lesion that predict the development of new surface disruption. MATERIALS AND METHODS One hundred eight asymptomatic individuals with 5...

While automation of signal and route setting is routine, the use of automation or decision support in disruption management processes is far less common. Such support offers significant advantages in optimising re-planning of both timetable and resources (crew and rolling stock), and has value in offering a 'shared view' of re-planning across the many actors manage disruption. If this vision is...