in this paper, distributed parameter process systems behavior is studied in frequency domain. based on the dominant gain concept that is developed for such studies, a method is presented to control distributed parameter process systems. by using dominant gain concept, the location of open loop zeros, resulted from the time delay parameter in the process model, were changed from the right half p...

In this paper, distributed parameter process systems behavior is studied in frequency domain. Based on the dominant gain concept that is developed for such studies, a method is presented to control distributed parameter process systems. By using dominant gain concept, the location of open loop zeros, resulted from the time delay parameter in the process model, were changed from the right half p...

in this paper a new method is introduced and investigated for removing the destabilizing effects of time-delay parameter in control loops. the concept of the method is taken from the knowledge concerning the dynamic behaviour of irrational transfer functions (ir-tf), which is discussed and investigated elswhere in frequency response domain and is explained briefly here. ir-tfs, which are well c...

p53 alterations in human tumors often involve missense mutations that may confer dominant-negative or gain-of-function properties. Dominant-negative effects result in inactivation of wild-type p53 protein in heterozygous mutant cells and as such in a p53 null phenotype. Gain-of-function effects can directly promote tumor development or metastasis through antiapoptotic mechanisms or transcriptio...