introduction: we intended to assess the accuracy of re-expressed modification of diet for renal disease (mdrd) and cockcroft-gault (cg) equations to estimate glomerular filtration rate (gfr) in chronic kidney disease in two different etiologies of acute renal failure (arf): acute tubular necrosis (atn) and acute glomerulonephritis (agn). methods: patients admitted for arf or the patients compl...

Designs of the double sampling (DS) X chart are traditionally based on the average run length (ARL) criterion. However, the shape of the run length distribution changes with the process mean shifts, ranging from highly skewed when the process is in-control to almost symmetric when the mean shift is large. Therefore, we show that the ARL is a complicated performance measure and that the median r...

The objective of this paper is to develop statistical methodology for non-inferiority hypotheses to censored, exponentially distributed time to event endpoints. Motivated by a recent clinical trial in depression, we consider a gold standard design where a test group is compared with an active reference and with a placebo group. The test problem is formulated in terms of a retention of effect hy...

In this present study the double layers structure model of extended Korteweg-de Vries(K-dV) equation will be obtained with the help of the reductive perturbation method, which admits a double layer structure in current plasma model. Then by using of new analytical method we obtain the new exact solitary wave solutions of this equation. Double layer is a structure in plasma and consists of two p...

Clomipramine is a tricyclic antidepressant. Different methods for determination of clomipramine hydrochloride in plasma have been described. Most of these procedures favor the use of acidic back-extraction in extraction procedure and HPLC as the analytical technique. In this study, the clomipramine extraction procedure was modified and a direct injection to the column was performed to shorten t...