Congenital leukemia is a rare disease which in clinically evident at birth or apparent within the first few weeks of life; The disease is more common in infants with downs syndrome.  We present a case of combined mongolism and congenital leukemia and reviewe some aspect of the disease. 

Downs syndrome constitutes to be the most common chromosomal disorder. Patients with Downs's syndrome are posted for several surgeries including dental procedures and even for facial reconstruction. They are associated with several congenital anomalies in different organ system. There is also increased incidence of atlanto axial instability and risk of spinal cord injury. These children are sus...

The analysis of Alzheimer's disease is an important topic of research because the results and findings help elucidate problems associated with aging as well as other diseases including Downs’ syndrome, Parkinson’s disease, dementia with Lewy bodies, Multiple Sclerosis, Amyotrophic Lateral Sclerosis,and infectious disease including NeuroAIDS. Here we review just a few points from an ever growing...

In the age of prenatal screening and early intervention even at the molecular level, much has been said about the politics of geneticisation, yet relatively little remains known about how this politics actually shapes people's experiences. In this exquisite book about the history of Downs syndrome, which won the 2013 Dingle Prize by the British Society for the History of Science, Wright shows u...