Statement of Purpose: Hyaluronic acid (HA) is a biodegradable, biocompatible, non-immunogenic, nontoxic, and non-inflammatory linear polysaccharide. HA has been used for various medical applications such as arthritis treatment, ocular surgery, tissue augmentation, drug delivery and tissue engineering [1]. In this work, HA has been extensively investigated as novel drug carriers for target speci...

Presynapticand postsynaptic glutamatergic modulation is associated with anti-depressant activity that takes several weeks to reach a maximal full effect [1]. Limiting mood elevating effects after single drug administration may be the result of compensatory synaptic processes [2, 3]. Therefore, using augmentation treatment with agents having presynapticand postsynaptic effects on the glutamaterg...

background breast augmentation is the most frequent procedure performed according to the 2009 quick facts report of the american society of plastic surgeons. this study presents the periareolar extra-glandular breast augmentation. methods from 2004 to 2010 among 32 female patients, peri-areolar incision was performed for breast augmentation. dissection was performed in subcutaneous plane toward...

introduction here we report an unusual case of massive stone formation in augmented urinary bladder. case presentation a 25-year-old man presented with recurrent urinary tract infection ten years after augmentation cystoplasty after a complex pelvic fracture urethral distraction defect. on evaluation by ultrasonography, x-ray, and computed tomography of abdomen showed large burden of stones in ...

When cyclophosphamide was administered to mice before immunization with syngeneic SV40 transformed cells, the specific immune response elicited, as was measured by in vitro 51Cr release assay was stronger and lasted longer when compared to the response generated in noncyclophosphamide-treated mice. The augmentation effect of the drug was dependent on cyclophosphamide concentration being optimal...

Graph classification, which aims to identify the category labels of graphs, plays a significant role in drug toxicity detection, protein analysis etc. However, limitation scale benchmark datasets makes it easy for graph classification models fall into over-fitting and undergeneralization. To improve this, we introduce data augmentation on graphs (i.e. augmentation) present four methods:random m...