introduction and aims: h. pylori has been implicated in peptic diseases, some with detrimental consequences such as ulcer or cancer. since considerable genetic heterogeneity has been observed within h. pylori population worldwide, it appears an ideal achievement to recruit pcr-based methods and design genetic markers which recognize isolates from normal and symptomatic individuals. in this stud...

background : many  helicobacter pylori strains express adhesin proteins that bind to specific  host-cell  macromolecule  receptors,  like sialic acid binding adhesion ( saba ).    saba-expressing  strains have been associated with gastric cancer  and  negatively  associated   with  duodenal   ulcers. the  aim  of  this study  was  to  determine   the  status  of   saba   gene  of   h.  pylori  ...

BACKGROUND/AIMS Gallbladder diseases can give rise to dyspeptic or colonic symptoms in addition to biliary pain. Although most biliary pain shows improvement after cholecystectomy, the fates of dyspeptic or colonic symptoms still remain controversial. This study as-sessed whether nonspecific gastrointestinal symptoms improved after laparoscopic cholecystectomy (LC) and identified the char-acter...

Dyspepsia is a digestive syndrome distinct from (although frequently overlapping with) gastro-oesophageal reflux disease (GORD) and irritable bowel syndrome (IBS), which is characterised by various combinations of painful and non-painful symptoms arising from the epigastrium. Dyspepsia can be secondary to a variety of diseases, but in most instances it is idiopathic. Helicobacter pylori infecti...

BACKGROUND Dyspepsia is a common syndrome and provides primary care physicians with a significant workload. To optimize the management of dyspepsia, several guidelines have been developed. OBJECTIVE The aim of this study was to determine the incidence of upper gastrointestinal diseases and their relationship to Helicobacter pylori infection in dyspeptic patients referred for upper endoscopy b...

background epidemiology of diseases changes over time with changes in socio-economic status, culture and health care systems. gastroesophageal reflux disease (gerd) and peptic ulcer disease (pud) are among the diseases whose epidemiology has changed over the past few decades in the west. studies addressing the trend of gerd and pud occurrence in iran are lacking. we aimed to look at the time tr...

The aims of this study were to determine the prevalence of cagA type in Helicobacter pylori isolated from dyspeptic patients in northeastern Thailand and to determine whether the pattern of cagA EPIYA motifs were associated with clinical outcomes. One hundred and forty-seven H. pylori-infected dyspeptic patients were enrolled, of whom 68 had non-ulcer dyspepsia (NUD), 57 peptic ulcer disease (P...

background â to investigate any possible relationship between serum leptin level and h. pylori infection in dyspeptic iranian adults. methods a total of 153 dyspeptic patients referring to  firoozgar hospital for esophagogastroduodenoscopy were enrolled in the study. serum leptin level was measured before endoscopy, after overnight fasting. two biopsy specimens were taken from antrum for each p...