Ewing family tumors (EFTs) and prostate carcinomas are characterized by rearrangement of ETS genes, most commonly FLI1 (EFTs) and ERG (prostate carcinomas). Previously, we characterized an antibody against ERG (EPR3864) for detecting ERG-rearranged prostate carcinoma. Because EPR3864 also cross-reacts with FLI1, we evaluated the usefulness of EPR3864 for discriminating EFTs from other small rou...

Ewing family tumors (EFTs) are small round blue cell tumors that show features of neuroectodermal differentiation. However, the histogenetic origin of EFTs is still a matter of debate. We used high-density DNA microarrays for the identification of EFT-specific gene expression profiles in comparison with normal tissues of diverse origin. We identified 37 genes that are up-regulated in EFTs compa...

Sustainable tourism and ecotourism have now been researched in depth for some years. This paper highlights that researchers still have only a limited understanding of what tourist behaviour can be considered as sustainable, and little consensus about who environment-friendly tourists (EFTs) actually are. This study reviews theoretical and empirical studies by tourism researchers, and explores w...

The present study classified global Ecosystem Functional Types (EFTs) derived from seasonal vegetation dynamics of the GIMMS3g NDVI time-series. Rotated Principal Component Analysis (PCA) was run on the derived phenological and productivity variables, which selected the Standing Biomass (approximation of Net Primary Productivity), the Cyclic Fraction (seasonal vegetation productivity), the Perm...

We systematically explore the space of scalar effective field theories (EFTs) consistent with a Lorentz invariant and local S-matrix. To do so we define an EFT classification based on four parameters characterizing 1) the number of derivatives per interaction, 2) the soft properties of amplitudes, 3) the leading valency of the interactions, and 4) the spacetime dimension. Carving out the allowe...

OBJECTIVE To evaluate the influence of fellowship training in endourology on different endourological procedures in a single institution. SUBJECTS AND METHODS The operative records of endourological and open surgeries were reviewed. Data analysed included numbers, types, and technical issues related to surgeries. The early study period ranged from September 1998 to September 2004, and the lat...

Drug resistance to therapeutic antibiotics poses a challenge to the identification of novel targets and drugs for the treatment of infectious diseases. Infections caused by Enterococcus faecalis are a major health problem. Thymidylate synthase (TS) from E. faecalis is a potential target for antibacterial therapy. The X-ray crystallographic structure of E. faecalis thymidylate synthase (EfTS), w...

In recent years, a “change in attitude” in particle physics has led to our understanding current quantum field theories as effective field theories (EFTs). The present paper is concerned with the significance of this EFT approach, especially from the viewpoint of the debate on reductionism in science. In particular, it is a purpose of this paper to clarify how EFTs may provide an interesting ca...

This essay considers the extent to which a concept of emergence can be associated with Effective Field Theories (EFTs). I suggest that such a concept can be characterized by microphysicalism and novelty underwritten by the elimination of degrees of freedom from a high-energy theory, and argue that this makes emergence in EFTs distinct from other concepts of emergence in physics that have appear...

Objectives Study the clinical characteristics of patients diagnosed with Ewing family tumors (EFTs) and survival analysis based on risk criteria and expression of the surface protein known as insulin-like growth factor (IGFR). Methods This was a retrospective cohort study based on clinical data from 77 patients diagnosed with EFTs treated by the Department of Pediatric Oncology at the Barreto...