نتایج جستجو برای: egfr
تعداد نتایج: 30143 فیلتر نتایج به سال:
conclusions these findings indicate that telbivudine, used in both monotherapy and combination therapy, improves the renal function of patients with chb. the improvements are particularly significant in patients at high renal risk. patients and methods this study included 336 chinese chb patients, who were selected from outpatients in tongji hospital. 44, 122, 66, 58, and 46 of these patients h...
سرطان مری پس از سرطان معده دومین و سومین سرطان شایع در مردان و زنان ایرانی است و تخمین زده می شود که از 35000 مورد مرگ سالیانه ناشی از سرطان که در ایران اتفاق می افتد حدود 5800 مورد مرگ ناشی از سرطان مری می باشد . این سرطان به انواع گوناگونی تقسیم می شود که دو نوع کارسینوم سلول سنگفرشی مری (escc) و آدنوکارسینوم مری (eac) آن بسیار رایج است. اگر این سرطان درمان نشود می تواند به گره های لنفی، استخ...
objective(s): our previous study showed that a newly designed tracer radioiodinated 6-(3-morpholinopropoxy)-7-ethoxy-4-(3'-iodophenoxy)quinazoline ([125i]pyk) is promising for the evaluation of the epidermal growth factor receptor (egfr) status and prediction of gefitinib treatment of non-small cell lung cancer. egfr is over-expressed and mutated also in glioblastoma. in the present study,...
introduction: malignant salivary gland tumors are rare entities. despite advances in surgery, radiation therapy and chemotherapy, the rate of the mortality and five-year survival has not been improved markedly over the last few decades. the activation of egfr- ras-raf signaling pathway contributes to the initiation and progression of many human cancers, promising a key pathway for therapeutic m...
Background:Epidermal growth factor receptor (EGFR) overexpression is a characteristic of several malignancies and could be considered as an excellent target for designing specific inhibitors such as anti-EGFR monoclonal antibodies for cancer therapy. Drawbacks exerted by large sizes of full-length antibodies have lead to the development of single chain antibodies, which benefit from having smal...
Background: Although evidence indicates that tobacco use is one of the risk factors for oral cancer, the relationship between opium addiction and oral cancer has not yet been evaluated. The present study was performed aiming to evaluate P53 and epidermal growth factor receptor (EGFR) expression in the gingival tissue of opium-dependent patients.Methods: 102 individuals (70 men and 32 women) wer...
Introduction: Epidermal growth factor receptor (EGFR) has been shown to play a critical role in tumor cell growth and its overexpression has been observed in many epithelial tumors. In the field of cancer vaccine research, displaying the peptide mimotope on the surface of phage particles has shown promising results. Methods: In this study using m13-PVIII phage display system, two constructs we...
Background Poly cystic ovarian syndrome (PCOS) is known as a common endocrine disorder in women at reproductive ages and may cause developmental abnormality in oocyte. ERK has found as a regulator protein of Gap junctions (GJ) function and the level of exchanges between two neighbors cells, for example oocyte and surrounding cumulus cells (CCs) in the mammalian ovary. Such exchange is essential...
conclusions fasting in the month of ramadan in two consecutive years, and during the hottest months, in riyadh, saudi arabia, did not adversely affect kidney graft function. objectives to investigate the effect of repeated ramadan fasting during the hottest months of the year on renal graft functions. patients and methods this was a prospective cohort study comparing two groups of renal transpl...
سابقه و هدف: سرطان ریه اختلالی است که به دلیل تغییرات ژنتیکی و اپی ژنتیکی ایجاد و باعث فعال شدن انکوژن ها و غیر فعال شدن ژن های سرکوب گر تومور آغاز می شود. هدف از این تحقیق بررسی کمی بیان ژن های EGFR و FGFR4 در نمونه خون افراد مبتلا به سرطان ریه نسبت به افراد سالم و بررسی نقش این دو ژن به عنوان بیومارکر جهت غربالگری می باشد. مواد و روش ها: این مطالعه مورد-شاهد بر روی 50 نمونه خون افراد مبتلا ب...
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