Introduction: Cancer is one of the main causes for mortality and morbidity in the world. Identifying epidemiology and the trend of esophageal cancer may be highly effective in related planning. The present study has been carried out with the aim of exploring the morbidity and trend of esophageal cancer in Iran. Methods: The present study is a type of repe...

background : esophageal cancer is the 7th most common cancer in iran. the northern part of the country shows the highest incidence for this malignancy. in this study we present some epidemiological and clinicopathological characteristics of patients with esophageal carcinoma in this region. methods : in a cross sectional study, 238 esophageal cancer patients were enrolled in a prospective study...

introduction: cigarette smoking and alcohol consumption have a well-known effect on the development of upper aerodigestive tract carcinomas, but such a role for opium is questionable. this study was designed to assess the correlation between opium inhalation and cancer of the larynx and upper esophagus. materials and methods: fifty eight patients with laryngeal cancer, ninety eight patients wit...

esophageal cancer is one of the most common malignancies in our country. patients often seek medical advice in advanced and inoperable stages or with cervical esophageal cancer, in which operation is accompanied by sever morbidity. in this conditions many of them cannot tolerate chemo-radiation, or refuse it. therefore radiotherapy is applied as a single modality in palliation of many patients ...

Background & Aims: Esophageal and gastric cancers are among prevalent cancers in the world and it is believed that nitrate and nitrite contaminations of drinking water are important factors in increasing the risk of these cancers. This study was designed to determine the correlations between these factors and upper gastrointestinal cancers. Methods: In this ecologic study, mean concentrations o...

Esophageal cancer (EC) is the sixth main cause of cancer death worldwide. Important genes associated with esophageal cancer include FOXO3, AKT, and GSK3β. Excessive FOXO3 expression inhibits the proliferation of cancer cells. The expression of AKT is involved in controlling cell growth in tumors. GSK3β activity is higher in cancer tissues. Given the effective role of cancer stem cells (CSCs) in...

esophageal cancer is one of the most common malignancies with a growing occurrence . it presently ranks ninth among the most frequent cancers in the world and the sixth leading cause of death from cancer . for a variety of reasons, the mainstream of patients with esophageal cancer is actually not suitable for esophagectomy. more than 50% have locally advanced unresectable or metastatic tumors a...

 Abstract Background: Esophageal cancer is one of the major malignancies, with various epidemiological aspects in recent years in developing countries, including increased prevalence and variations of pathologic patterns. This may be due to increasing rates of Barrett’s esophagus, gastroesophageal reflux, smoking and obesity. This study was performed from 1991 to 2005 in order to evaluate vario...

abstract background: esophageal anastomosis leaks continue to be a significant cause of morbidity and mortality after esophagectomy. the purpose of the present study was to identify the predisposing factors of esophageal anastomotic leakage. materials and methods: 95 patients who underwent surgical resection for esophageal or cardia cancer were included for the study. the mean age of the patien...