introduction and aims: both observational and experimental studies have shown that higher selenium status reduces the risk of upper gastrointestinal cancers in selenium deficient populations. recent cancer registry data have shown very different rates of esophageal cancer (ec) and gastric cancer (gc) in four provinces of iran, namely ardabil, mazandaran, golestan, and kerman. the aim of this st...

background: chemokine receptors have been shown to play an important role in the development and metastatic spread of various malignancies. in this study, the gene expression profile of some key chemokine receptors involved in metastasis has been investigated in esophageal and breast cancer cell lines.   methods: in a descriptive study, gene expression profile of ccr1, ccr6, ccr7, ccr9, cxcr1, ...

background little is known about the possible influence of demographic and histological risk factors on the survival of patients with esophageal and gastric cancer. objectives based on the available registry and follow-up information, this study compares 1-5 year survival rate of gastric and esophageal cancer. patients and methods through a concurrent (prospective) cohort study, all 366 patient...

introduction: as one of the most common cancers among head and neck malignancies, cancer of the oral cavity probably has some variations in countries with a high prevalence of esophageal cancer.  materials and methods: patients with oral cavity cancer who were treated at two tertiary referral centers from january 1999 to january 2009 were included in this study. in addition to demographic data,...

background: in northeastern iran there is an area of high incidence of esophageal cancer which is populated by residents of turkmen ancestry. several environmental risk factors for esophageal cancer have been proposed, but the roles of familial and genetic factors have not been studied extensively in the turkmen population. materials and methods: we evaluated the importance of familial risk fac...

introduction: esophageal and gastric cancers are among the most common cancers in iran. usually survival of these cases is poor despite of treatment. here we studied outcome of these cases in our center to have an estimation of general prognosis of patients. methods: in this retrospective study, we reviewed the data of patient's files before treatment, including cancer stage at diagnosis, types...

background:â  northeastern iran has a high incidence for squamous cell esophageal carcinoma (escc). the aim of the study is to the assess relationship between celiac disease (cd) and escc. materials and methods:â  this was a two-part, cross-sectional, case-control study performed during 2006-2011 in gonbad, â golestan, iran. serum iga anti-tissue transglutaminase antibody levels were measured f...

Background & Aims: Esophageal Cancer is the sixth fatal cancer in the world. Squamous and adenocarcinoma account for 95% of esophageal cancer. The expression of EGFR has a role in the pathophysiology of epidermal-based malignancies such as esophageal cancer. EGFR is also an important criterion in the evaluation of disease staging and prognosis. The aim of this study was to survey the prevalence...