methods: we examined 170 formalin-fixed paraffin-embedded samples from esophageal squamous cell carcinoma patients. all subjects live in mazandaran province, a region with high incidence rate of esophageal cancer and have become known as the “asian esophageal cancer belt”. samples were tested for hpv-dna by my09/11 and gp5+/6+ general primers using nested pcr. results: of the 170 escc samples, ...

Single nucleotide polymorphisms (SNPs) in TERT may be associated with susceptibility to esophageal cancer. In this study, we analyzed the association between TERT SNPs and risk of esophageal cancer in 386 esophageal cancer patients and 495 healthy subjects from the Xi'an area of China. Of the four SNPs examined, rs10069690 and rs2242652 were correlated with esophageal cancer risk. Additionally,...

introduction: the molecular mechanisms involved in pathogenesis of esophageal cancer have been the main concern of several studies. in this study, we aimed to investigate the changes of serum prooxidant-antioxidant balance (pab) value as a redox index, as well as serum c-reactive protein (crp) compared to healthy control group. materials and methods: in a cross-sectional study, blood samples we...

Esophageal cancer incidence rates have been increasing over the past years and survival remain low. According to Global Cancer Observatory, 3.1% of new cases consists esophageal 5.5% deaths was due cancer. Histologic classification comprises either squamous cell carcinoma (SCC) or Adenocarcinoma. Other types are reported be uncommon. We present a case 33-year old male admitted progressive dysph...

background only a few studies in western countrieshave investigated the association between gastroesophageal reflux disease(gerd) and mortality at the general population level and they have shown mixedresults. this study investigated the association between gerd symptoms andoverall and cause-specific mortality in a large prospective population-based studyin golestan province, iran. methods base...

abstract background: esophageal cancer is one of the major malignancies, with various epidemiological aspects in recent years in developing countries, including increased prevalence and variations of pathologic patterns. this may be due to increasing rates of barrett’s esophagus, gastroesophageal reflux, smoking and obesity. this study was performed from 1991 to 2005 in order to evaluate variou...

Esophageal cancer is the eighth most common cancer and causes the sixth highest cancer-related mortality worldwide. The 5-year survival of patients suffering from esophageal cancer in either advanced stage or metastasis is less than 20%. MicroRNAs are small, well conserved, non-coding RNA molecules that either repress translation or promote mRNA degradation based on the degree of complementary ...

background and objective: esophageal cancer especially squamous cell carcinoma (scc) is one of the most common gastro intestinal malignancies in north part of iran (khorasan). the standard treatment for esophageal cancer is surgical resection, but its outcome remains poor. then, the oncologists try to treat this cancer with sandwich protocols especially neo-adjuvant chemo-radiotherapy. several ...

background & aim: esophageal cancer is one of the main common causes of death. the high prevalence of esophageal cancer in northern iran is an important public health problem. the main aim of this paper was to assess the factors affecting survival of  atients with esophageal cancer in neighbor provinces around the caspian sea using weibull mixture cure model and mixture cure model based on a no...

This study divided patients with esophageal cancer and multiple primary cancers into two groups, a head and neck cancer (HNC) group and a non-head and neck cancer (NHNC) group. These groups were then evaluated on the basis of clinical and pathological studies. Among 92 patients with esophageal cancer as one of multiple primary cancers, 38 (41.8%) were assigned to the HNC group. The following ch...