نتایج جستجو برای: experimental autoimmune

تعداد نتایج: 761587  

Journal: :iranian journal of allergy, asthma and immunology 0
zahra zamanzadeh department of medical genetics, national institute of genetic engineering and biotechnology (nigeb), tehran, iran ghasem ahangari department of medical genetics, national institute of genetic engineering and biotechnology (nigeb), tehran, iran mitra ataei department of medical genetics, national institute of genetic engineering and biotechnology (nigeb), tehran, iran samie pouragahi qazvin university of medical sciences, qazvin, iran seyed massood nabavi department of neurology , shahed university of medical sciences, tehran, iran mehdi sadeghi department of medical genetics, national institute of genetic engineering and biotechnology (nigeb), tehran, iran

multiple sclerosis (ms) is an autoimmune disease in which auto-reactive t cells react with self-antigens expressed in the central nervous system (cns). the main cause of ms is unknown. nonetheless, the most probable theory is based on molecular mimicry, which suggests that some infections can activate t cells against brain auto-antigens like myelin proteolipid protein (plp) and initiate the dis...

Journal: :acta medica iranica 0
zehtab t rafieii tehranie s yazdanparast r

tyrosinase has been recognized as a major autoantign in human vitiligo. here we have shown that experimental autoimmune vitiligo can be induced by intradermal injection of mushroom tyrosinase emulsified in complete freund’s adjuvant in c57bl/6 mice. the onse of vitiligo was characterized by hair hypopigmentation and total melanocyte depletion in the basal layer of the epidermis. our results con...

Journal: :iranian biomedical journal 0
طاهره زهتاب tahere zehtab راضیه یزدان پرست razieh yazdanparast شهناز رفیعی shahnaz rafieii

experimental autoimmune vitiligo was induced by the intradermal injection of the purified mushroom tyrosinase emulsified in complete freund’s adjuvant (cfa) in female c57bl/6 mice. the onset of vitiligo was characterized by hair hypopigmentation and total melanocyte depletion in the basal layer of the epidermis. oral administration of semipurified mushroom tyrosinase prevented experimental auto...

2007
Vijay K. Kuchroo Samia J. Khoury Bing Zhu Yoshio Bando Sheng Xiao Kaiyong Yang Ana C. Anderson

Journal: :European journal of public health 2006
Karien Stronks Johan P Mackenbach

OBJECTIVES Many initiatives have been taken in European countries that are designed to reduce inequalities in health. However, the effects of only a very few of these initiatives have been assessed. The main aim of a Dutch research and development programme was to systematically investigate and evaluate interventions aimed at reducing inequalities in health. In this paper, we report on this inv...

Journal: :iranian journal of allergy, asthma and immunology 0
soodeh razeghi jahromi ms research center, neuroscience institute, tehran university of medical sciences, tehran, iran and department of clinical nutrition and dietetics, faculty of nutrition and food technology, shahid beheshti university of medical sciences, tehran, iran and shefa neuroscience research centre, khatam-alanbia hospital, tehran, iran amir ghaemi department of virology, school of medicine, golestan university of medical sciences, gorgan, iran and shefa neuroscience research centre, khatam-alanbia hospital, tehran, iran akram alizadeh cellular and molecular research center, shahrekord university of medical sciences, shahrekord, iran fatemeh sabetghadam school of veterinary medicine, ferdowsi university of mashhad, mashhad, iran hedieh moradi tabriz department of pathology, sina hospital, tehran university of medical sciences, tehran, iran mansoureh togha headache department, iranian center of neurological research, neuroscience institute, tehran university of medical sciences, tehran, iran

several religions recommend periods of fasting. one of the most frequently asked questions of ms patients before the holy month of ramadan is weather fasting might have an unfavorable effect on their disease course. this debate became more challenging after the publication of experimental studies suggesting that calorie restriction prior to disease induction attenuates disease severity. we cond...

Journal: :iranian journal of pathology 2015
ameneh ghaffarinia cyrus jalili ali mostafaie shahram parvaneh nafiseh pakravan

background and objectives: multiple sclerosis is an inflammatory disease of the central nervous system. this is due to migration of peripherally activated lymphocytes to central nervous system leading to inflammatory lesions. however, liver has an anti-inflammatory microenvironment. myelin expression in the liver of transgenic mice suppresses inflammatory lesions within central nervous system. ...

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