نتایج جستجو برای: f10

تعداد نتایج: 1231  

F10

Journal: :Arthropod Management Tests 2012

2014
Timothy S. Pardee Kristin Stadelman Jamie Jennings-Gee David L. Caudell William H. Gmeiner

F10 is an oligonucleotide based on the thymidylate synthase (TS) inhibitory 5-fluorouracil (5-FU) metabolite, 5-fluoro-2'-deoxyuridine-5'-O-monophosphate. We sought to determine the activity of F10 against preclinical models of acute lymphoblastic leukemia (ALL). F10 treatment resulted in robust induction of apoptosis that could not be equaled by 100 fold more 5-FU. F10 was more potent than Ara...

Journal: :Bioscience, biotechnology, and biochemistry 2010
Siti Salwa Abd Gani Mahiran Basri Mohd Basyaruddin Abdul Rahman Anuar Kassim Raja Noor Zaliha Raja Abd Rahman Abu Bakar Salleh Zahariah Ismail

Formulations containing engkabang fat and engkabang fat esters, F10 and E15 respectively were prepared using a high-shear homogenizer, followed by a high-pressure homogenizer. Both formulations were stable at room temperature, at 45 degrees C, and after undergoing freeze-thaw cycles. The particle sizes of F10 and E15 after high pressure were 115.75 nm and 148.41 nm respectively. The zeta potent...

2017
Yali Song Wei Cao Xi Zhu Zhuolin Qiu Xiaoping Yang Jing Liu Ruoting Xu Weizhuang Yuan Song Quan

F10 is a novel hydatidiform mole (HM)-associated gene that was initially identified during a study into the pathogenesis of HMs. However, the role of the F10 gene requires further investigation. Our, previous studies have indicated that F10 may be involved in the malignant transformation of HMs and the development of certain types of adenocarcinoma, and that the overexpression of F10 may lead t...

Journal: :Journal of virology 2004
Patricia Szajner Andrea S Weisberg Bernard Moss

Temperature-sensitive mutants of vaccinia virus, with genetic changes that map to the open reading frame encoding the F10 protein kinase, exhibit a defect at an early stage of viral morphogenesis. To further study the role of the enzyme, we constructed recombinant vaccinia virus vF10V5i, which expresses inducible V5 epitope-tagged F10 and is dependent on a chemical inducer for plaque formation ...

Journal: :Toxicon : official journal of the International Society on Toxinology 2014
Mary A Aranda-Souza Franco A Rossato Rute A P Costa Tiago R Figueira Roger F Castilho Miriam C Guarniere Erika S Nunes Luana C B B Coelho Maria T S Correia Anibal E Vercesi

BlL, a galactose-binding C-type lectin purified from Bothrops leucurus snake venom, exhibits anticancer activity. The current study was designed to elucidate the cellular mechanisms by which BlL induces melanoma cell death. The viabilities of B16-F10 melanoma cells and HaCaT keratinocytes treated with BlL were evaluated. Necrotic and apoptotic cell death, cytosolic Ca(2+) levels, mitochondrial ...

2008
S J TAI R W HERZOG P MARGARITIS V R ARRUDA K CHU J A GOLDEN P A LABOSKY K A HIGH

BACKGROUND Activated factor X (FXa) is a vitamin K-dependent serine protease that plays a pivotal role in blood coagulation by converting prothrombin to thrombin. There are no reports of humans with complete deficiency of FX, and knockout of murine F10 is embryonic or perinatal lethal. OBJECTIVE We sought to generate a viable mouse model of FX deficiency. METHODS We used a socket-targeting ...

Journal: :Biocell : official journal of the Sociedades Latinoamericanas de Microscopia Electronica ... et. al 2005
M T Teruel R C Catalano J A Cabodevila S S Callejas

Embryo development depends on maternal and embryonic factors. When occurs in vitro, embryos secrete factors that stimulate their development. The purpose of this study was to investigate the possible effects of embryos at morula stage on mouse embryo development in vitro. To obtain conditioned media (CM), morulas were cultured in groups of 5 (CM5) or 10 (CM10) in microdrops of Ham-F10 culture m...

Journal: :Veterinary parasitology 2017
Nichapat Yurayart Morakot Kaewthamasorn Sonthaya Tiawsirisup

Avian malaria caused by Plasmodium gallinaceum is an important mosquito-borne disease. Eradication of this disease remains problematic since its competent vectors are diverse and widely distributed across the globe. Several mosquito species were implicated as competent vectors for this parasite. However, studies on vector competence for P. gallinaceum remain limited. In this study, vector compe...

Journal: :Journal of virology 1999
S Takase-Yoden R Watanabe

The efficiency of receptor-mediated entry of pseudotyped virus carrying the surface protein (SU) of clone A8, a neuropathogenic variant of Friend murine leukemia virus (FrMLV), to rat glial cell line F10 was 1 order of magnitude greater than that of pseudotyped virus carrying SU of nonneuropathogenic FrMLV clone 57. Introduction of the gene coding for ecotropic MLV receptor on F10 cells (F10-ec...

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