BACKGROUND The purpose of this study was to examine the levels of occupational stress and physical symptoms among family medicine residents and investigate the effect of subscales of occupational stress on physical symptoms. METHODS A self-administered questionnaire survey of 1,152 family medicine residents was carried out via e-mail from April 2010 to July 2010. The response rate was 13.1% a...

Health[1] Health[1]Bacteria [2]Children's health [3]illness [4]immune system [5]Stress [6]Viruses [7]Norway [8] Forskning.no [9] High levels of stress in a family can undermine a child?s immune system, making it easier for viruses and bacteria to do their worst. Our immune system protects us from bacteria and viruses. But intense or long-lasting psychological stress can have a negative effect o...

Keratin 16 (K16) is a cytoskeletal scaffolding protein highly expressed at pressure-bearing sites of the mammalian footpad. It can be induced in hyperproliferative states such as wound healing, inflammation and cancer. Here we show that the inactive rhomboid protease RHBDF2 (iRHOM2) regulates thickening of the footpad epidermis through its interaction with K16. K16 expression is absent in the t...

An important question facing the juvenile justice system is the appropriate placement of adolescents who are adjudicated for a sexual offense. In the face of increasing questions about the advisability of institutionalization, there is understandable pressure to determine which juveniles can be successfully managed and treated in the community. The decision about whether they can be safely retu...

BACKGROUND The objective of the study was to the determine of neuroticism, requirements of the labor market and work-family conflict while exploring consequences of various aspects of job stress in occupationally active parents. MATERIAL AND METHODS The investigations covered 159 females and 154 males from families where both parents are occupationally active and bring up at least one child a...

p53 is an important tumor suppressor gene, which is stimulated by cellular stress like ionizing radiation, hypoxia, carcinogens, and oxidative stress. Upon activation, p53 leads to cell-cycle arrest and promotes DNA repair or induces apoptosis via several pathways. p63 and p73 are structural homologs of p53 that can act similarly to the protein and also hold functions distinct from p53. Today m...

The present study was designed to assess and compare parenting stress and family burden in mothers of children with disabilities and children without disability. For this purpose, a multi group design was adopted which consisted of five groups of mothers viz. mothers of children with mental disability, mothers of children with both mental and physical disability, mothers of children with physic...

The native fold of inhibitory serpins (serpin proteinase inhibitors) is metastable and therefore does not represent the most stable conformation that the primary sequence encodes for. The most stable form is adopted when the reactive centre loop (RCL) inserts, as the fourth strand, into the A b -sheet. Currently a serpin can adopt at least four more stable conformations, termed the cleaved, del...

During dire conditions, the channelling of resources into reproduction ensures species preservation. This strategy of survival through the next generation is particularly important for plants that are unable to escape their environment but can produce hardy seeds. Here, we describe the multiple roles of OXIDATIVE STRESS 2 (OXS2) in maintaining vegetative growth, activating stress tolerance, or ...