background: in most cancer cases, the treatment choice for a pregnant patient is radiotherapy. in these patients, the abdomen is usually not exposed therefore fetus exposure is due to peripheral dose (pd). the purpose of this study was to estimate the fetal dose (the maximum pd in each pregnancy stage) for modalities available and to fabricate and evaluate a generally applicable fetal shield. m...

background: because of the adverse effects of ionizing radiation on fetuses, prior to radiotherapy of pregnant patients, fetal dose should be estimated. fetal dose has been studied by several authors in different depths in phantoms with various abdomen thicknesses (at). in this study, the effect of maternal at and depth in fetal dosimetry was investigated, using peripheral dose (pd) distributio...

background: pregnant women are sometimes exposed to ionizing radiation in radiology examinations for various reasons. in such cases, the radiation dose to the conceptus and subsequent risks should be estimated. objective: the purpose of this study was the calculation and presentation of fetal dose and subsequent risks resulted from different x-ray examinations. materials and methods: an analyti...

Background: In most cancer cases, the treatment choice for a pregnant patient is radiotherapy. In these patients, the abdomen is usually not exposed therefore fetus exposure is due to peripheral dose (PD). The purpose of this study was to estimate the fetal dose (the maximum PD in each pregnancy stage) for modalities available and to fabricate and evaluate a generally applicable fetal ...

Background. Although radiation exposure is of great concern to expecting patients, little information is available on the fetal radiation dose associated with prophylactic internal iliac artery balloon occlusion (IIABO). Here we estimated the fetal radiation dose associated with prophylactic IIABO in Caesarean section (CS). Cases. We report our experience with the IIABO procedure in three conse...

A 42-year-old woman at 29 weeks gestation via in vitro fertilization who presented with eight metastatic brain lesions received Gamma Knife stereotactic radiosurgery (GKSRS) at our institution. In this study, we report our clinical experience and a general procedure of determining the fetal dose from patient-specific treatment plans and we describe quality assurance measurements to guide the sa...

Acute, high-dose exposure to endotoxin lipopolysaccharide (LPS) in preterm fetal sheep can trigger periventricular white matter lesions (PVL), in association with severe hypotension/hypoxemia and significant mortality. Intriguingly, however, chronic or repeated exposure to LPS can induce tachyphylaxis. We therefore tested the hypothesis that progressive, acute on chronic fetal infection would b...

BACKGROUND Use of high-dose inhalational anesthesia during open fetal surgery may induce maternal-fetal hemodynamic instability and fetal myocardial depression. The authors' preliminary human retrospective study demonstrated less fetal bradycardia and left ventricular systolic dysfunction with lower dose desflurane supplemented with propofol and remifentanil IV anesthesia (SIVA). In this animal...

UNLABELLED One aim of the current study was to determine normalized dose data for maternal radiosensitive organs and embryo/fetus from 256-slice CT pulmonary angiography (CTPA) performed on pregnant patients suspected of having pulmonary embolism. A second aim was to provide reliable maternal and fetal doses and associated radiation cancer risk estimates from 256-slice CTPA and lung perfusion s...

Mathai S, Booth LC, Davidson JO, Drury PP, Fraser M, Jensen EC, George S, Naylor A, Gunn AJ, Bennet L. Acute on chronic exposure to endotoxin in preterm fetal sheep. Am J Physiol Regul Integr Comp Physiol 304: R189–R197, 2013. First published December 12, 2012; doi:10.1152/ajpregu.00388.2012.—Acute, high-dose exposure to endotoxin lipopolysaccharide (LPS) in preterm fetal sheep can trigger peri...