are incurable diseases characterised by high inter-and intra-tumor heterogeneity (ITH), diffuse brain infiltration and treatment resistance. Over the last fifteen years, studies at the interface between stem cell biology and cancer research have established the existence of cancer stem-like populations in GBM and other brain tumors (reviewed in [1]). These data have been accompanied by speculat...

Motivated by the goal of establishing stochastic and information theoretic foundations for the study of intelligence and synthesis of intelligent machines, this thesis probes several topics relating to hidden state stochastic models. Finite Growth Models (FGM) are introduced. These are nonnegative functionals that arise from parametrically-weighted directed acyclic graphs and a tuple observatio...

Abstract In functionally graded heat-resisting material, the volume fraction of constituents varies and continuously, these are examined for high temperature engineering applications. By spatial distribution thermal behaviour FGMs is strongly influenced. Thus, determination becomes a critical part in FGM design given loading condition specification. present work, averaging estimation approach v...

Composite materials are promising materials, which should exhibit an improve on several aspects of the physical properties such as mechanical, thermal, electrical etc.. A composite material is a system of materials composed of two or more components randomly mixed and bonded on a macroscopic scale. For example, metal-alloys Silicon carbides such as Aluminum Silicon Carbide (AlSiC) is made up of...

Abstract. The evolution of Friction Stir Consolidation (FSC) from recycling towards upcycling technique proved to be one the excellent solid-state methods for manufacturing functionally graded billets. Multi-material Functional Graded Materials (FGMs) represent a novel class materials characterized by gradual change in properties and functions which can tailored enhance components performance. ...

This paper presents numerical simulations of transient dynamic fracture behaviors and quasi-static crack growth in cracked functionally graded composites using the enhanced extended consecutive-interpolation quadrilateral element (XCQ4). The mechanical properties functional are assumed to vary continuously spatial coordinates. In terms XCQ4 modeling, only one function ramp type (either linear, ...

Image processing, power engineering, robotics, industrial automation etc., have all found successful uses for artificial intelligence (AI) techniques such as neural networks (ANN) and neuro-fuzzy logic (FL). In this study, an adaptive inference system (ANFIS) modelling of machine learning (ML) has been implemented to estimate the tribological properties functionally graded materials (FGM). Thes...

In this paper a study on the vibration of thin cylindrical shells with ring supports and made of functionally graded materials (FGMs) composed of stainless steel and nickel is presented. The properties are graded in the thickness direction according to a volume fraction power-law distribution.The cylindrical shells with ring supports which are arbitrarily placed along the shell and impose zero ...

An analytical method for predicting elastic–plastic stress distribution in a cylindrical pressure vessel has been presented. The vessel material was a ceramic/metal functionally graded material, i.e. a particle–reinforcement composite. It was assumed that the material’s plastic deformation follows an isotropic strain-hardening rule based on the von-Mises yield criterion, and that the vessel was...