BACKGROUND/AIMS Therapeutic vaccination is a new approach to treat patients with chronic hepatitis B virus infection. We have used the woodchuck model to examine the efficacy and safety of this approach. METHODS Seven woodchucks chronically infected with woodchuck hepatitis virus were immunized with surface antigen from this virus, purified from plasma, in conjunction with a peptide named FIS...

Intelligent energy management has become one of the major research fields in electrical engineering. It constitutes an important tool for efficient planning and operation of power systems and its significance has been intensifying particularly, because of the recent movement towards open energy markets and the need to assure high standards on reliability. Hybrid neuro-fuzzy paradigms have recen...

Intrusion Detection System (IDS) provides additional security for the most vulnerable Mobile Adhoc Networks (MANET). Use of Fuzzy Inference System (FIS) in the design of IDS is proven to be efficient in detecting routing attacks in MANETs. Clustering is a vital means in the detection process of FIS based hybrid IDS. This study describes the design of such a system to detect black hole attack in...

Continental ice sheets are a key component of the Earth's climate system, but their internal dynamics need to be further studied. Since the last deglaciation, the northern Eurasian Fennoscandian Ice Sheet (FIS) has been connected to the Black Sea (BS) watershed, making this basin a suitable location to investigate former ice-sheet dynamics. Here, from a core retrieved in the BS, we combine the ...

senescence has long been established as a stable and irreversible growth arrest, which plays an important role in tumor suppression and tissue repair. It can be induced by various stimuli, including telomere shortening, oncogene activation and oxidative stress. We recently demonstrated that cell-cell fusion is a previously unidentified trigger for inducing cellular senescence [1]. This work was...

One day, you will discover a new adventure and knowledge by spending more money. But when? Do you think that you need to obtain those all requirements when having much money? Why don't you try to get something simple at first? That's something that will lead you to know more about the world, adventure, some places, history, entertainment, and more? It is your own time to continue reading habit....

A fault section in Korean distribution networks is generally determined as a between switch with indicator (FI) and without an FI. However, the existing method cannot be applied to distributed generations (DGs) due false FIs that are generated by currents flowing from load side of location. To identify make applicable, this paper proposes determine utilizing artificial neural network (ANN) mode...

The genome DNA of Escherichia coli is associated with about 10 DNA-binding structural proteins, altogether forming the nucleoid. The nucleoid proteins play some functional roles, besides their structural roles, in the global regulation of such essential DNA functions as replication, recombination, and transcription. Using a quantitative Western blot method, we have performed for the first time ...