background: exposures to lead above the threshold value of 50–60 μg/dl have been linked to diminished semen quality parameters. worldwide, the lead exposure has been diminished during the last years. therefore, it has become of a great concern to examine the effects of lead exposures on semen quality at low levels of exposure. objective: to evaluate the effect of low level (<20 μg/dl) blood lea...

the use of flow cytometry in the clinical laboratory has grown substantially in the past decade. flow cytometric analysis provides a rapid qualitative and quantitative description of multiple characteristics of individual cells. for example, it is possible to detect the cell size and granularity, aspects of dna and rna content and the presence of cell surface and nuclear markers which are used ...

among the numerous nanosized drug delivery systems currently under investigation, carbon nanotubes (cnts), regardless of being single or multiple-walled, offer several advantages and are considered as promising candidates for drug targeting. despite the valuable potentials of cnts in drug delivery, their toxicity still remains an important issue. after the pegylation of single-walled cnts (swcn...

objective: cutaneous leishmaniasis is an endemic infectious disease considered to be a crucial health problem in many countries, including iran. as such, there is a need for new medications with few side effects. in the present research we have studied the effect of artimisinin on  leishmania major (l. major) and cell death in vitro. methods: a specific number of promastigotes of l. major were ...

background: lactoferrin (lf) is a glycoprotein, a member of the transferrin family.from ten known mechanisms of anti-cancer chemoperotecive compounds, lf alone, has six of these functions and inhibits cancer. in this study, the effect of lactoferrin purified from bovine colostrum was studied as an anti-cancer agent on esophageal cancer cell line. materials and methods: bovine colostrum were col...

background: the purpose of the present in vitro study was to evaluate the effect of long term storage of conventional platelet concentrates (pcs) on major platelet receptors cd42b and cd41/cd61 by flow cytometry method and also measuring the overall platelet procoagulant activity status using platelet factor 3 (pf3) assay. materials and methods: six random units of conventional platelet concent...

background: human cd34 is a transmembrane glycoprotein which is expressed in human hematopoietic stem cells (hscs) and the small- vessel endothelial cells of a variety of tissues. cd34 plays a critical role as a marker for diagnosis and classification of leukemia. anti cd34 antibodies are used for isolation and purification of hscs from bone marrow, peripheral blood and cord blood. objective: t...

background: flow cytometry is a rapid, sensitive, and reliable method for determination of bacterial viability. here we assayed the capability of flow cytometry to detect helicobacter pylori viable cells in both forms of spiral and coccoid. methods: viable bacteria stained with rhodamin 123 and fluoresced with laser beam of 488nm. the rate of rh123 absorption was determined in both forms of bac...