introduction during the process photodynamic therapy (pdt), bleaching of photosensitizer induced by irradiation and generation of reactive oxygen species (ros) can provide some information concerning the efficiency of treatment. since gold nanoparticles (gnps) have been highlighted as efficient drug delivery systems, in this study, by utilizing gnps conjugated with 5 aminolevulinic acid (5-ala-...

Background and Objectives: The inability of classic fluorescence-activated cell sorting to single cancer cell sorting is one of the most significant drawbacks of this method. The sorting of cancer cells in microdroplets significantly influences our ability to analyze cancer cell proteins. Material and Methods: We adapted a developed microfluidic device as a 3D in vitro model to sorted MCF-7 c...

glucose 6-phosphate dehydrogenase (g6pd) from streptomyces aureofaciens was purified and denatured in 6 m urea. denaturation led to complete dissociation of the enzyme into its inactive monomers, 98% loss of the enzyme activity, about 30% decrease in the protein fluorescence and a 10 nm red shift in the emission maximum. dilution of urea-denatured enzyme resulted in regaining of the enzyme acti...

bronchial asthma is the common chronic inflammatory disease and is characterized by chronic airway inflammation, airway remodeling, and airway hyperreactivity (ahr). aim of this study was to investigate the effects of mitochondrial atp-sensitive potassium channels (mitokatp) on the proliferation and secretion of human airway smooth muscle cells (hasmcs). hasmcs were treated with the serum from ...

background: this cross sectional comparative study was performed to compare the mean fluorescence intensity of cluster of differentiation 45 between healthy individuals and patients with acute lymphoblastic leukemia. patients and methods: thirty three healthy individuals (mean age 11 years) and 41 patients with b cell acute lymphoblastic leukemia (mean age 7 years) were enrolled in the study in...

background: glycowithanolides (withaferin a), is one of the main withanolides active principle isolated from plant withania somnifera and is claimed that it possess the aphrodisiac, sedative, rejuvenate and life prolonging properties. objective: in the present investigation, antioxidant activity of active principles of withania somnifera was tested against d-galactose induced oxidative stress i...

Abstract. RAMSES is the operational spectrometric fluorescence and Raman lidar at Lindenberg Meteorological Observatory. It employs three spectrometers, with UVA spectrometer (378–458 nm spectral range) being latest to be implemented in 2018. The extends measurement range shorter wavelengths than previously accessible, its water vapor measurements can corrected for effects. First new experiment...