background: there are some reports in the literature showing that hypothalamus synthesizes and secretes amino acid neurotransmitters. according to several studies, elevated serum levels of gamma-amino butyric acid (gaba), a potent inhibitory neurotransmitter, have recently been implicated in the pathogenesis of neural diseases. the purpose of this research was to estimate the effects of curcumi...

N-Phthaloyl GABA was administrated daily (50 mg/Kg body weight-i.p) to Wistar rats for 21 days and circadian rhythms of thiobarbituric acid reactive substances (TBARS) and antioxidants such as reduced glutathione (GSH), catalase (CAT) and superoxide dismutase (SOD) were studied under constant light (LL) conditions. Delayed acrophase of TBARS and advanced acrophase of antioxidants (GSH, CAT and ...

Changes in extra and intracellular neurotransmitter amino acids concentration in the early stage of acute cerebral ischemia have been reported. In this the study, serum level of gamma aminobutyric acid (GABA) and L-Arginine in acute ischemic stroke patients was assessed. 60 patients with acute ischemic stroke and sixthy healthy volunteers as a control group were assessed. Serum GABA was measure...

gamma aminobutyric acid (gaba) is one of the inhibitory neurotransmitters that may have the ability torelieve the intensity of stress. heat stress remains a major threat for duck production in summer in most areas of china. the current study was conducted to investigate the effect of dietary gaba on performanceparameters and plasma metabolites of heat exposed ducks. two thousand cherry valley d...

Glutamate and γ-aminobutyric acid (GABA) are the two main neurotransmitters in human brain. The balance between their excitatory inhibitory functions is crucial for maintaining brain’s physiological functions. Disturbance of glutamatergic or GABAergic neurotransmission leads to serious health problems including neurodegeneration, affective sleep disorders. Both GABA glutamate involved control s...

Gamma-aminobutyric acid (GABA) has several health-promoting qualities, leading to a growing demand for natural GABA production via microbial fermentation. The GABA-producing abilities of the new Tetragenococcus halophilus (THSK) isolated from commercial soy sauce moromi were proven in this investigation. Under aerobic conditions, isolate produced 293.43 mg/L after 5 days cultivation, compared 2...

Some bacteria decarboxylate amino acids as a means of resisting acid stress. It is mechanism commonly used by in fermented dairy products. The decarboxylation histidine to histamine occurs frequently some types cheese, but high concentrations can be harmful consumers. Not all products are, however, undesirable. GABA, the product glutamate, has positive effects on human health. Although and GABA...

Background: Hypertension is considered an independent risk factor for cardiovascular mortality in diabetic patients. The present study was designed to determine the role of gamma amino butyric acid B (GABAB) receptor and L-arginine (L-Arg) in GABA-induced vasorelaxation in normal and streptozotocin-induced diabetic rat vessels. Methods: Diabetes was induced by a single i.p. injection of strepto...

Abstract Gamma-aminobutyric acid (GABA) and glutamate are the primary neurotransmitters responsible for modulating excitatory inhibitory signalling within human brain. Dysfunctional GABAergic glutamatergic has been identified as a key factor in range of neuropsychiatric conditions; hence measurement modulation these neurometabolites is important improving our understanding conditions treatment ...

changes in extra and intracellular neurotransmitter amino acids concentration in the early stage of acute cerebral ischemia have been reported. in this the study, serum level of gamma aminobutyric acid (gaba) and l-arginine in acute ischemic stroke patients was assessed. 60 patients with acute ischemic stroke and sixthy healthy volunteers as a control group were assessed. serum gaba was measure...