Freeze-drying and gamma irradiation are the techniques widely use in tissue banking for preservation and sterilization of tissue grafts respectively. However, the effect of these techniques on biomechanical properties of bovine pericardium is poorly known. A total of 300 strips of bovine pericardium each measured 4 cm 1 cm were used in this study to evaluate the effect of freeze-drying on biome...

Transfusion-associated graft-versus-host disease can be prevented by treating cellular blood products with gamma irradiation. A wide range of gamma irradiation dose levels has been used in routine practice. We used limiting dilution analysis, which measures clonable T cells, to assess the influence of 500 to 3,000 cGy of gamma irradiation delivered from a 137Cs source on T cells when delivered ...

In recent times efforts are being made to improve the productivity of bambara groundnut. Studies were initiated (i) to characterise and evaluate landraces and to select superior ones for irradiation, (ii) to induce genetic variation through gamma irradiation and (iii) to use biotechnological approaches to shorten the generation cycle. The results of the study indicated that gamma irradiation in...

OBJECTIVES Cervical cancer is a malignancy that is the second most common cause of death from cancer in women throughout the world. Paederus beetle (Paederus fuscipes) extract (PBE), contains bioactive compounds such as pederine which has cytotoxic properties and blocks DNA and protein synthesis at very low concentrations. In this investigation we tried to determine the effects co-treatment wit...

An azobenzene-modified gamma-cyclodextrin stationary phase (Az gamma-CDSP) was prepared and its photo- and temperature-responses for the retention of perylene and pentacene were investigated using a mixture of methanol and water as the mobile phase in micro-HPLC. The retention of perylene slightly increased, whereas that of pentacene significantly decreased by UV light irradiation to Az gamma-C...

UV-induced replication arrest in the xeroderma pigmentosum variant (XPV) but not in normal cells leads to an accumulation of the Mre11/Rad50/Nbs1 complex and phosphorylated histone H2AX (gamma-H2AX) in large nuclear foci at sites of stalled replication forks. These complexes have been shown to signal the presence of DNA damage, in particular, double-strand breaks (DSBs). This finding suggests t...

The impacts of UV irradiation, gamma irradiation, and a combination of both on Escherichia coli inactivation in primary and secondary wastewater effluents were investigated. UV doses of 35 and 62 J/m(2) were required for a 1-log inactivation of E. coli in the primary and secondary wastewater samples, respectively. A gamma dose of 170 Gy (J/kg) was required for a 1-log inactivation of E. coli in...

Gamma irradiation is one of the most important physical mutagen used for inducing beneficial as well as harmful cytogenetic effects in many crop plants. The cytogenetic changes occurring due to the storage of Lathyrus sativus L. seeds after gamma irradiation were examined during the present study. Mitotic index showed a dose dependant decrease while the dose and duration of treatments increased...

Melanins are natural pigments distributed in living organisms and they are responsible for pigmentation of surface structure. In the present work, gel exclusion chromatography, spectrophotometric, and dielectric relaxation techniques were used to characterize DOPA melanin before and after irradiation with 60 Co gamma rays in the range of 5 to 50 Gy. The results show that the studied melanin is ...

Background: Currently available radioprotectors are poorly tolerated in man and the general use of aminothiols is compromised by their side effects. This study was carried out to test and compare the radioprotective potential of cimetidine and famotidine against lethally gamma irradiated NMRI mice. Materials and Methods: Adult male NMRI mice in groups of 10 were exposed to various doses of gamm...