The characteristic constituents of Ganoderma lucidum, such as polysaccharides, triterpenoids, nucleic acids, and small proteins, have been found and proved to have many special pharmacological properties. Mice have been used to extensively investigate the effects of G. lucidum. Experiments with mice investigating the effects of concentrates of G. lucidum have never been reported. The purpose of...

Ganoderma lucidum (G. lucidum) is a medicinal mushroom renowned in East Asia for its potential biological effects. To enable a systematic exploration of the genes associated with the various phenotypes of the fungus, the genome consortium of G. lucidum has carried out an expressed sequence tag (EST) sequencing project. Using a Sanger sequencing based approach, 47,285 ESTs were obtained from in ...

Phylogenetic relationship of Ganoderma species confining to Tamil Nadu was assessed by three molecular markers viz., internal transcribed spacer region (ITS) 1 and 2, β-tubulin and ATP synthase subunit 6 (atp6). Forty-three isolates representing 11 species of Ganoderma were identified from ITS rDNA sequence data. The nucleotide variations found in the ITS region were suitable for discriminating...

The present study aims to investigate the antimicrobial and antitumor properties of Ganoderma lucidum fruit bodies grown under tropical habitat. The phytochemicals present in Ganoderma sp. DKR1 were analyzed and identified as saponins, tannins, terpenoids and phlobatannins. The bioactive compounds in Ganoderma sp. DKR1 were extracted using the solvents (ethyl acetate and chloroform). Its antimi...

The sequence-characterized amplified region (SCAR) is a valuable molecular technique for the genetic identification of any species. This method is mainly derived from the molecular cloning of the amplified DNA fragments achieved from the random amplified polymorphic DNA (RAPD). In this study, we collected DNA from 10 species of Ganoderma mushroom and amplified the DNA using an improved RAPD tec...

Lignin is probably one of the most recalcitrant compounds synthesized by plants. This compound is degraded by few microorganisms. White-rot fungi have been extensively studied due to its powerful ligninolytic enzymes. Ganoderma lucidum is one such organism that can degrade lignin and hence it was isolated and screened qualitatively by guaiacol plate assay. Spectrophotometric enzyme assays were ...

The morphology of Ganoderma lucidum BCCM 31549 mycelium in a repeated-batch fermentation (RBF) was studied for exopolysaccharide (EPS) production. RBF was optimised for time to replace and volume to replace. G. lucidum mycelium showed the ability to self-immobilise and exhibited high stability for repeated use in RBF with engulfed pellets. Furthermore, the ovoid and starburst-like pellet morpho...

The objectives of this study were to evaluate applicability of food waste compost (FWC) as a substrate for cultivation of Ganoderma lucidum, Lentinula edodes, and Pholiota adipose, and to determine contents of Ca, Mg, Na, and K in fruiting bodies (FB). FB yield per substrate in FWC-free controls was 53 ± 4 g/kg for G. lucidum, 270 ± 90 g/kg for L. edodes, and 1,430 ± 355 g/kg for P. adipose. Su...