نتایج جستجو برای: gastric cancer
تعداد نتایج: 973988 فیلتر نتایج به سال:
metformin has recently been introduced as an anti-cancer agent. in this study, we evaluated the effect of metformin and metformin/cisplatin on human gastric mkn-45 cell line. when we used metformin alone, it could inhibit proliferation and induce apoptosis, but it diminish anti-proliferative effects of cisplatin when they are used in combination. further, we checked mrna levels of survivin, mto...
isolating melittin from bee venom and evaluating its effect on proliferation of gastric cancer cells
background and purpose: gastric cancer (gc) is one of the most common cancers worldwide and in iran. as conventional therapies such as surgery and chemotherapy are invasive with adverse effects, current studies are important as they are conducted to find natural compounds with few adverse effects. in this study, melittin with 26 amino acids was isolated and purified from bee venom and its effec...
conclusions this study suggests that the vaca pcr can be very useful in diagnosis, treatment, and follow-up of patients with gastritis and pud. the pcr assay and clo test can complement and confirm each other in identification and eradication of cancer-related strains of h. pylori. the exclusion of patients with suspected achlorhydria from the study is likely a reason for the lack of false posi...
gastric adenocarcinoma is the second leading cause of death due to cancer in the world and in advanced stages the prognosis is poor with current therapies. over-expression of her-2/neu has been seen in several cancers such as gastric cancer and its expression is associated with poor prognosis. the aim of this study is to evaluate the over-expression of her-2/neu in gastric biopsy samples of pat...
advanced gastric cancer, a very rare complication of common variable immunodeficiency: a case report
background : common variable immunodeficiency (cvid) is associated with a broad spectrum of symptoms related to infections, chronic lung diseases, autoimmune diseases, and tumors; however, solid tumors are rare complications of cvid and gastric cancer, specially, has been reported very rarely. case presentation : the present case report describes a 28 years old known case of cvid male, who was ...
background: attempts for early detection of gastric cancer have recently focused on host's genetic susceptibility factors and gene-environment interactions. we have, herein, studied the association of mthfr c677t single nucleotide polymorphism (snp) and its interaction with helicobacter pylori infection, smoking, age and gender on the risk of gastric cancer among an iranian population. met...
Background and purpose: Gastric cancer is the second most common cause of cancer worldwide and despite huge advances in treatments, the chance of survival is very low even in surgery cases. Having a genetic predisposition plays an important role in cancer development. Polymorphisms in the NQO1(NAD(P)H Quinone dehydrogenase 1) gene could affect the activity of the gene and also the susceptibilit...
Background and purpose: Gastric cancer is one of the most common gastrointestinal cancers in the world. Gastric cancer is the most common cancer in north of Iran. Interleukin-17F (IL-17F) is a pro-inflammatory cytokine expressed by a novel subset of CD4+ Th cells (Th-17), and it causes the occurrence and strengthening the inflammatory response. This study aimed to assess the association betwe...
Introduction & Objective: Gastric cancer is the forth common cancer and second cause of death. Surgery is the primary treatment of gastric cancer and chemotherapy and radiotherapy is used as supplementary treatments. The aim of this study is estimation of survival and affected fac-tor in the patients with gastric cancer after surgery in Hamadan province. Materials & Methods: All patients with p...
Abstract Background and Objective: BabA2 and Hpa genes are involved in adherence of Helicobacter pylori (H.pylori) to gastric mucosal tissue. This study aimed to investigate the frequency of these genes in isolates of H. pylori from gastric biopsies and their relationship with gastritis, peptic ulcer and gastric cancer. M...
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