background: opioid peptides and their receptors are present in the majority of body tissues including gastrointestinal tract.  heroin is one of the opioid derivatives that abuse increasingly today.  so far, there is no study on the effect of acute heroin administration on gastric acid and pepsin secretion.   objective:  to define the effect of the acute heroin consumption on basal and vagal-sti...

Background: Opioid peptides and their receptors are present in the majority of body tissues including gastrointestinal tract.  Heroin is one of the opioid derivatives that abuse increasingly today.  So far, there is no study on the effect of acute heroin administration on gastric acid and pepsin secretion. Objective:  To define the effect of the acute heroin consumption on basal and vagal-stimu...

Introduction: The effect of esophageal distension (ED) on gastric motility has been well documented, but a few investigations have been carried out on the effect of ED on gastric secretion. The aim of this study was to investigate the effect of ED on gastric acid and pepsin secretion and the mechanism(s) involved. Methods: Male adult Wistar rats (200-240 g) were anesthetized with urethane (1...

introduction: the effect of esophageal distension (ed) on gastric motility has been well documented, but a few investigations have been carried out on the effect of ed on gastric secretion. the aim of this study was to investigate the effect of ed on gastric acid and pepsin secretion and the mechanism(s) involved. methods: male adult wistar rats (200-240 g) were anesthetized with urethane (1.2 ...

noise is considered as one of the most severe sources of environmental and workplace constraints. many noise effects are well known on immune function, hormonal levels, cardiovascular and respiratory systems. in this study, our aim is to evaluate the effects of traffic noise exposure on basal and stimulated gastric pepsin secretion. 48 male rats were exposed to traffic noise (86 db) for a short...

objective(s) the liver has major role in the organism homeostasis, interactions with other systems, synthesis and metabolism of bile production, drug detoxification and hormone inactivation. cholestasis can be defined as an impairment of the bile flow which can lead to hepatocytes necrosis and finally cirrhosis. some studies reported a gastric acid secretion reduction in cirrhotic subjects, whi...

Objective(s) The liver has major role in the organism homeostasis, interactions with other systems, synthesis and metabolism of bile production, drug detoxification and hormone inactivation. Cholestasis can be defined as an impairment of the bile flow which can lead to hepatocytes necrosis and finally cirrhosis. Some studies reported a gastric acid secretion reduction in cirrhotic subjects, wh...

thyroid hoemones effect gastric acid and pepsin secretion.however exact machanism(s) are not clear.this study was performed to compare the effect of vagal stimulation on acid an pepsin secretion in hypothyroid,hyperthyroid and control rars.each group consisted of 8 male and female rats(N-mari) weighing 246+_9 gr.hypo and hyperthyroid states were induced by administretion of methimazol (50mg/l i...

Objective(s) Gastric ulceration is induced by various forms of stress like surgery, ischemia and trauma. The female sex has more resistance to stress and the gastrointestinal lesions happen fewer than male sex. The purpose of this study was to evaluate the role of estradiol and progesterone on the gastric acid and pepsin levels following traumatic brain injury (TBI) induction. Materials and M...

objective(s) gastric ulceration is induced by various forms of stress like surgery, ischemia and trauma. the female sex has more resistance to stress and the gastrointestinal lesions happen fewer than male sex. the purpose of this study was to evaluate the role of estradiol and progesterone on the gastric acid and pepsin levels following traumatic brain injury (tbi) induction. materials and met...