background the importance of sialic acid binding adhesin (saba) as a new outer membrane protein in gastroduodenal diseases has been recognized. the prevalence rate of saba gene varies in different geographic areas. objectives the aim of this study was to determine the frequency of saba gene in helicobacter pylori (h. pylori) strains isolated from different clinical outcomes in tehran, iran. pat...

the raini cashmere goat is one of the iranian goat breeds with a high economic value on international markets due to its high production and high quality. the bmp15 gene regulates granulose cell proliferation and differentiation by promoting granulosa cell mitosis, suppressing follicle-stimulating hormone receptor expression, and stimulating the kit ligand expression. this gene plays a pivotal ...

conclusions the at1r a1166c polymorphism appeared not to be associated with the presence of acs in the population studied. background there are very limited data for iranian populations on the predisposing genetic factors for acute coronary syndrome (acs). results there was no statistical difference in the genotype frequency of patients and healthy subjects with regard to age and gender (p > 0....

the ability to taste phenylthiocarbamide (ptc), a bitter organic compound, described as a bimodal autosomal trait is widely used to know the heritable trait in both genetic and anthropological studies. the present study was carried out to analyze the prevalence of ptc taste sensitivity and to determine the gene frequencies among some muslim populations of uttar pradesh, india. this study has so...

 Background: Spinal muscular atrophy (SMA) is the second most common lethal autosomal recessive disease. It is a neuromuscular disorder caused by degenerative of lower motor neurons and occasionally bulbar neurons leading to progressive limb paralysis and muscular atrophy. The SMN1 gene is recognized as a SMA causing gene while NAIP has been characterized as a modifying factor for the clinical ...

Schizophrenia is a mental disorder characterized by abnormal social behavior and failure to understand reality. The aim of this study was to determine the relation between FOLH1 and DISC1 genes polymorphism in patients with schizophrenia in Iran. In this study, 50 patients with schizophrenia and 50 healthy controls were evaluated. PCR-RFLP was used for FOLH1 gene and Tetra-ARMS for the DIS...

Background: In this study we aimed at detecting the enterotoxin A and B gene of S. aureus in clinical samples of patients attending health centers in Zahedan using molecular methods. Materials and Methods: A cross-sectional study was carried out in which 40 samples of S. aureus were obtained from patients in a hospital in Zahedan, Iran. Following the biochemical tests, Identifications were c...

spinal muscular atrophies (smas) are one of the more common autosomal recessive and single gene disorders. they are heterogeneous disorders, both in phenotypic and genotypic aspects. prevalence of these disorders are about 1 of every 6000 to 25000 live born babies in different ethnicities. in some chinese population prevalence of disease reported to be 1 in 50000. if it was true, carrier freque...

The objective of this study was to evaluate myostatin (MSTN) gene by polymerase chain reaction -restriction fragment length polymorphism (PCR-RFLP) and sequencing methods in four goat breeds including Mohabadi, Markhoz, Lori and Bital breeds. A573 bp fragment of MSTN gene was amplified by PCR. A new 5 bp deletion in 5`UTR (206TTTTA) of the MSTN gene was directly identified by sequencing. The AA...