background and objective: serum creatinine is the most used endogenous marker of glomerular filtration rate (gfr), but it also has multiple limitations. therefore, some surrogate gfr markers, such as beta trace protein, have been introduced for gfr estimation. the aim of our study was to estimate gfr by serum beta trace protein using three available equations and compare them to dtpa gfr as the...

Background and Objective: Serum creatinine is the most used endogenous marker of glomerular filtration rate (GFR), but it also has multiple limitations. Therefore, some surrogate GFR markers, such as beta trace protein, have been introduced for GFR estimation. The aim of our study was to estimate GFR by serum beta trace protein using three available equations and compare them to DTPA GFR as the...

background: diabetic nephropathy (dn) is one of the most important complications of diabetes mellitus. now-a-days, cystatin c (cysc) is introduced as a new marker for diagnosis of renal damages; however, use of this marker in clinical laboratories is still controversial. the present study was aimed to evaluate the diagnostic value of serum cysc for early detection or monitoring treatment of kid...

The occurrence of chronic kidney disease is underestimated in both human and veterinary medicine. Glomerular filtration rate (GFR) is considered the gold standard for evaluating kidney function. However, GFR assessment is time-consuming and labor-intensive and therefore not routinely used in practice. The commonly used indirect GFR markers, serum creatinine (sCr) and urea, are not sufficiently ...

ABSTRACT In this issue of Clinical Kidney Journal, Stehlé and colleagues demonstrate that estimation glomerular filtration rate (GFR) by use creatinine a measure, total lumbar muscle cross-sectional area, reflecting the mass an individual, is superior to GFR-estimating equations based upon demographic variables. The report et al. demonstrates one solution interference in estimate GFR. This was ...

The assessment of the glomerular filtration rate (GFR) is the most commonly used test of renal function. The accepted reference procedure employs an exogenous clearance marker whilst the most popular test is that of serum or plasma creatinine. All of these tests have limitations, although the surrogate endogenous markers are the most practical. Cystatin C, a low molecular weight protein which c...

background glomerular filtration rate (gfr) is widely estimated by serum creatinine based equations such as cockcroft-gault (cg) standardized for body surface, and an abbreviated formula derived from mdrd (modification of diet in renal disease) study. however, some studies suggested that creatinine based estimation of gfr formula can be replaced by cystatin c based formula. objectives the aim o...

Background: Measurement of glomerular filtration rate (GFR) and monitoring of it in any patient on nephrotoxic drugs is very important. Recently, cystatin C (cys-C) has been introduced as a better marker for determining and monitoring renal function than creatinine especially in a mild decrease of GFR. This study was done to assess the change of GFR measurement based on serum Cys-C and creatini...