نتایج جستجو برای: goat mesenchymal stem cells

تعداد نتایج: 1528943  

Journal: :iranian journal of basic medical sciences 0
mohamadreza baghaban eslaminejad stem cell department, cell science research centre, royan institute, acecr, tehran, iran hamid nazarian stem cell department, cell science research centre, royan institute, acecr, tehran, iran fahimeh falahi stem cell department, cell science research centre, royan institute, acecr, tehran, iran leila taghiyar stem cell department, cell science research centre, royan institute, acecr, tehran, iran mohamad taghi daneshzadeh royan animal facility, karaj, iran

objective(s) mesenchymal stem cells (mscs) from large animals as goat which is genetically more closely related to human have rarely been gained attentions. the present study tried to isolate and characterize mscs from goat bone marrow. materials and methods fibroblastic cells appeared in goat marrow cell culture were expanded through several subcultures. passaged-3 cells were then differentiat...

Journal: :international journal of hematology-oncology and stem cell research 0
khushnuma cooper regenerative medicine group, reliance life sciences pvt. ltd., dhirubhai ambani life sciences centre, r-282, ttc area of midc, thane-belapur rd. rabale, navi mumbai - 400701, maharashtra, india. viru shah regenerative medicine group, reliance life sciences pvt. ltd., dhirubhai ambani life sciences centre, r-282, ttc area of midc, thane-belapur rd. rabale, navi mumbai - 400701, maharashtra, india. nupur sapre regenerative medicine group, reliance life sciences pvt. ltd., dhirubhai ambani life sciences centre, r-282, ttc area of midc, thane-belapur rd. rabale, navi mumbai - 400701, maharashtra, india. ekta sharma regenerative medicine group, reliance life sciences pvt. ltd., dhirubhai ambani life sciences centre, r-282, ttc area of midc, thane-belapur rd. rabale, navi mumbai - 400701, maharashtra, india. chetna mistry regenerative medicine group, reliance life sciences pvt. ltd., dhirubhai ambani life sciences centre, r-282, ttc area of midc, thane-belapur rd. rabale, navi mumbai - 400701, maharashtra, india. chandra viswanathan regenerative medicine group, reliance life sciences pvt. ltd., dhirubhai ambani life sciences centre, r-282, ttc area of midc, thane-belapur rd. rabale, navi mumbai - 400701, maharashtra, india.

background: umbilical cord tissue is a very rich source of mesenchymal stem cells. instead of discarding this source we are banking the tissue along with cord blood for possible future cell based applications. the cord tissue needs to be transported and stored properly in order for it to be good enough for cell isolation at a later date. in this paper we have carried out a validation study to d...

Journal: :avicenna journal of medical biotechnology 0

background: the definitive endoderm (de) differentiation using the undefined media and non-human feeders can cause contaminations in the generated cells for therapeutic applications. therefore, generating safer and more appropriate de cells is needed. this study compared five different methods to establish an appropriate method for inducing an efficient de differentiation from human induced plu...

Journal: :iranian journal of immunology 0
mandana mohyeddin bonab hematology-oncology & bmt research centre sepideh yazdanbakhsh department of neurology, shariati hospital jamshid lotfi iranian ms society kamran alimoghaddom hematology-oncology & bmt research centre fatemeh talebian immunogenetics research centre, medical sciences/university of tehran, tehran, iran farnaz hooshmand iranian ms society ardeshir ghavamzadeh

background: mesenchymal stem cells (mscs) with their potential to differentiate into mesodermal and non-mesodermal lineages have several immunomodulatory characteris-tics. these properties make them promising tools in cell and gene therapy. objective: to evaluate the potential therapeutic applications of autologous msc in improving clinical manifestations of ms patients. methods: ten patients w...

Journal: :international journal of hematology-oncology and stem cell research 0
abdolreza ardeshiry lajimi stem cell biology department, stem cell technology research center, tehran, iran. majid farshdousti hagh division of laboratory hematology and blood banking, faculty of medicine, tabriz university of medical sciences, tabriz, iran. najmaldin saki research center of thalassemia & hemoglobinopathy, ahvaz jundishapur university of medical sciences, ahvaz, iran. esmaeil mortaz division of pharmacology and pathophysiology, utrecht institute for pharmaceutical sciences, faculty of sciences, utrecht university, utrecht, the netherlands. masoud soleimani hematology department, faculty of medical science, tarbiat modares university, tehran, iran. fakher rahim toxicology research center, ahvaz jundishapur, university of medical sciences, ahvaz, iran.

multiple sclerosis is an inflammatory disease of the central nervous system in which t cells experience a second phase of activation, which ultimately leads to axonal demyelination and neurological disability. the recent advances in stem cell therapies may serve as potential treatments for neurological disorders. there are broad types of stem cells such as neural, embryonic, mesenchymal and hem...

Journal: :iranian journal of immunology 0
neda mousavi niri department of immunology mansooreh jaberipour shiraz institute for cancer research, shiraz university of medical sciences, shiraz, iran mahboobeh razmkhah shiraz institute for cancer research, shiraz university of medical sciences, shiraz, iran abbas ghaderi department of immunology mojtaba habibagahi department of immunology

background: several studies have demonstrated the immunosuppresive effects of mes-enchymal stem cells (mscs) in allogeneic or mitogenic interactions. cell-cell contact inhibition and secretion of suppressive soluble factors have been suggested in this re-gard. objective: to investigate if adipose derived mscs could inhibit jurkat lym-phoblastic leukemia t cell proliferation during coculture. me...

Journal: :archives of trauma research 0
serkan akpancar department of orthopedic surgery, gulhane military hospital, ankara, turkey; department of orthopedic surgery, gulhane military medicine academy, ankara, turkey. tel: +90-5443229700, fax: +90-3124045500 oner tatar department of orthopedic surgery, air force academy kasımpaşa military hospital, istanbul, turkey hasan turgut department of orthopedic surgery, bursa military hospital, bursa, turkey faruk akyildiz department of orthopedic surgery, gulhane military hospital, ankara, turkey safak ekinci department of orthopedic surgery, agri military hospital, agri, turkey

conclusions large amounts of preclinical studies have been made of stem cells and there is an increasing interest to perform these studies within the human population but preclinical studies are insufficient; therefore, much more and efficient studies should be conducted to evaluate the efficacy and safety of stem cells. context musculoskeletal injuries may be painful, troublesome, life limitin...

Journal: :iranian biomedical journal 0
mehri fayazi mojdeh salehnia saeideh ziae

background: the aim of this study was to investigate the percentage of the stem cells population in human endometrial tissue sections and cultured cells at fourth passage. methods: human endometrial specimens were divided into two parts, one part for morphological studies and the other part for in vitro culture. full thickness of human normal endometrial sections and cultured endometrial cells ...

Fahimeh Falahi Hamid Nazarian Leila Taghiyar Mohamad Taghi Daneshzadeh Mohamadreza Baghaban Eslaminejad,

Objective(s) Mesenchymal stem cells (MSCs) from large animals as goat which is genetically more closely related to human have rarely been gained attentions. The present study tried to isolate and characterize MSCs from goat bone marrow. Materials and Methods Fibroblastic cells appeared in goat marrow cell culture were expanded through several subcultures. Passaged-3 cells were then different...

Journal: :iranian biomedical journal 0
fatemeh amiri sedigheh molaei marzie bahadori fatemeh nasiri mohammad reza deyhim mohammad ali jalili

background: mesenchymal stem cells (mscs) have been recently received increasing attention for cell-based therapy, especially in regenerative medicine. however, the low survival rate of these cells restricts their therapeutic applications. it is hypothesized that autophagy might play an important role in cellular homeostasis and survival. this study aims to investigate the regenerative potentia...

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