نتایج جستجو برای: goat mesenchymal stem cells

تعداد نتایج: 1528943  

Mohammadreza Alijani, Moosa Javdani, Rasool Rahimi Junqani,

Spinal cord injury (SCI) is a neurologic disorder that have a significant impact on quality of life, life expectancy, and economic burden. SCI leads to irreversible neuronal loss and ultimately leads to paralysis. Mesenchymal stem cells (MSCs) are a promising source for cellular therapy because they have possessed the capacity of self-renewal and differentiation to several distinct mesenchymal ...

Journal: :modares journal of medical sciences: pathobiology 2011
majid farshdousti hagh mehrdad noruzinia yousef mortazavi masood soleimani saeid kaviani

objective: zoledronic acid as a main treatment for osteoporosis has an important role in differentiation of mesenchymal stem cells. however, mechanism of osteoblastic differentiation induction by zoledronic acid is not well understood until now. in this research we evaluate zoledronic acid effect on methylation status of runx2 and dlx5 promoters. materials and methods: after isolation and expa...

Journal: :veterinary research forum 2013
mohamadreza baghaban eslaminejad nasrin fallah

in vitro expansion of mesenchymal stem cell (mscs) into large number is necessary for their application in cell-based treatment of articular cartilage defects. on the other hand, some studies have indicated that bio (6-bromoindirubin-3-oxime) possesses mitogenic effects on cell culture. the objective of the present study was to examine the effect of bio on in vitro expansion and chondrogenic di...

Journal: :veterinary research forum 2015
somayeh naderi malihe akbarzadeh niaki nasser mahdavi shahri maryam moghaddam matin masoud fereidoni

the aim of this study was to investigate the interactions between rat intestine decellularized scaffold and human adipose derived mesenchymal stem cells. rat large intestine was dissected in fragments and decellularized by physicochemical methods. the scaffolds were loaded by human adipose derived mesenchymal stem cells expressing green fluorescent protein. microscopic sections were prepared fr...

Journal: :journal of basic research in medical sciences 0
roohollah mirzaee khalilabadi blood transfusion research center, high institute for research and education in transfusion medicine, tehran, iran fatemeh yari blood transfusion research center, high institute for research and education in transfusion medicine, tehran, iran naser amirizadeh blood transfusion research center, high institute for research and education in transfusion medicine, tehran, iran mahin nikougoftar blood transfusion research center, high institute for research and education in transfusion medicine, tehran, iran arezoo oodi blood transfusion research center, high institute for research and education in transfusion medicine, tehran, iran

introduction: recognition of human leukocyte antigens (hla) is of importance for hematopoietic stem cell transplantation. any hla-mismatches between the donor and recipient can cause graft rejection or other complications. in hla-typing experiments, usage of hla-known reference cells accompany with hla-unknown samples is obligatory. some international centers represent these cells with high exp...

Journal: :the journal of tehran university heart center 0
shahram rabbani tehran heart center, tehran university of medical sciences, tehran, iran masoud soleimani tarbiat modares university, tehran, iran. mohammad sahebjam tehran heart center, tehran university of medical sciences, tehran, iran. mohammad imani iran polymer and petrochemical institute, tehran, iran. seyed mahdi nassiri faculty of veterinary medicine, university of tehran, tehran, iran. amir atashi stem cell and tissue engineering research center, shahroud university of medical sciences, shahroud, iran.

background: myocardial infarction is the main cause of death worldwide. angiogenesis, a promising new therapy for the treatment of diffuse coronary artery disease, shows a poor response to conventional revascularization techniques. this study focused on improving myocardial function using endothelial cells (ecs) and mesenchymal stem cells (mscs) in a sheep animal model. methods: acute myocardia...

Journal: :anatomical sciences journal 0
mahmoud mofid , faculty of medicine, baqiyatallah university of medical science seyed homayoon sadraie department of anatomical sciences, faculty of medicine, baqiyatallah university of medical sciences, tehran, iran.سازمان اصلی تایید شده: دانشگاه علوم پزشکی بقیه الله (baqiyatallah university of medical sciences) hossein imani faculty of medicine, baqiyatallah university of medical sciencesسازمان اصلی تایید شده: دانشگاه علوم پزشکی بقیه الله (baqiyatallah university of medical sciences) giti torkaman , faculty of medical sciences gholamreza kaka , neuroscience research center mohammad reza naghii faculty of public health

introduction: although, the effect of direct intra-articular injection of bone marrow stem cells (bmscs) on the repair of articular cartilage and the effect of elaeagnus angustifolia extract on pain relief in patients with osteoarthritis have been investigated, no studies has been conducted to compare the effects of these two therapeutic methods on the mechanical properties of articular cartila...

Journal: :anatomical sciences journal 0
tahereh foroutan organization mohamad zaman kasaie department of animal biology, faculty of biological sciences, kharazmi university, tehran, iran.

introduction: iiron oxide nanoparticles (io np) have an increasing number of biomedical applications. to date, the potential cytotoxicity of these particles remains an issue of debate. little is known about the cellular interaction or toxic effects of io np on differentiation of stem cells. the aim of the present study was to investigate the possible toxic role of different doses of io np in di...

Journal: :iranian journal of allergy, asthma and immunology 0
mohsen saeidi department of immunology, school of medicine, golestan university of medical sciences, gorgan, iran and department of immunology, school of medicine, tehran university of medical sciences, tehran, iran ahmad masoud department of immunology, school of medicine, tehran university of medical sciences, tehran, iran yadollah shakiba department of immunology, school of medicine, tehran university of medical sciences, tehran, iran jamshid hadjati department of immunology, school of medicine, tehran university of medical sciences, tehran, iran mandana mohyeddin bonab department of immunology, school of medicine, tehran university of medical sciences, tehran, iran mohammad hossein nicknam department of immunology, school of medicine, tehran university of medical sciences, tehran, iran and molecular immunology research center, tehran university of medical sciences, tehran, iran

the wharton’s jelly of the umbilical cord is believed to be a source of mesenchymal stem cells (mscs) which can be therapeutically applied in degenerative diseases. in this study, we investigated the immunomodulatory effect of umbilical cord derived- mesenchymal stem  cells (uc-mscs) and  bone  marrow-derived-mesenchymal stem  cells (bm-mscs) on differentiation, maturation, and endocytosis of m...

Journal: :acta medica iranica 0
bagher larijani endocrinology and metabolism research center, endocrinology and metabolism research institute, tehran university of medical sciences, tehran iran. hamidreza aghayan cgmp grade stem cell facility, chronic diseases research center, endocrinology and metabolism population sciences institute, tehran university of medical sciences, tehran, iran. parisa goodarzi school of nursing and midwifery, iran university of medical sciences, tehran, iran. fereshteh mohamadi-jahani department of biology, payame noor university, tehran, iran. abbas norouzi-javidan brain and spinal cord injury research center, cellular fanavaran knowledge-based organization, tehran university of medical sciences, tehran, iran. ahmad reza dehpour department of pharmacology, school of medicine, tehran university of medical sciences, tehran, iran.

in this study, our aim was to produce a generation of gmp-grade adipose tissue-derived mesenchymal stem cells for clinical applications. according to our results, we fulfill to establish consistent and also reproducible current good manufacturing practice (cgmp) compliant adipose tissue-derived mesenchymal stem cells from five female donors. the isolated cells were cultured in dmem supplemented...

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