Systemic magnesium homeostasis in mammals is primarily governed by the activities of the TRPM6 and TRPM7 cation channels, which mediate both uptake by the intestinal epithelial cells and reabsorption by the distal convoluted tubule cells in the kidney. In the nematode, C. elegans, intestinal magnesium uptake is dependent on the activities of the TRPM channel proteins, GON-2 and GTL-1. In this p...

three one-day workshops were held in Gaithersburg, Maryland. Each was attended by about 30 computational biologists, mathematicians, and computer scientists who were experts in the respective workshop areas. The first workshop discussed data infrastructure needs for the Genomes to Life (GTL) program with the objective of identifying current gaps and defining the infrastructure required for the ...

Gas-to-liquid (GTL) fuel is regarded as a promising alternative diesel fuel. It can be used either directly as a diesel fuel or in blends with petroleum-derived diesel or biodiesel. This study investigated the fuel properties, engine performance and exhaust emissions of B5 diesel, GTL fuel and their blends. The main fuel properties of the blended fuels showed a linear variation with the fractio...

Current world capacity of hydrocarbon liquefaction is around 400,000 barrels per day, providing a marginal share of the global liquid fuel supply. This study performs a broad review of technical, economic, environmental and supply chain issues related to coal-to-liquids (CTL) and gas-to-liquids (GTL). We find three issues predominate. First, significant amounts of coal and gas would be required...

this paper presents an economic evaluation of gas to liquids (gtl) project using “south-pars” gas field of iran based on the latest actual performing gtl projects. iran has the world’s largest reserves of natural gas and can satisfy the projected long-term market demand of gtl products which have lower pollution and higher quality than refinery products. the results of cost-benefit analysis sho...

The nematode Caenorhabditis elegans contains over 20 genes for TRP (transient receptor potential) channels which include members of all of the subclasses identified in mammalian cells. These proteins include three members of the TRPM (TRP melastatin) family: gon-2 (abnormal gonad development), gtl-1 (gon-2-like 1) and gtl-2. Although studies of these genes are at an early stage, we are beginnin...

Register Transfer Level (RTL) synthesis method in clocked designs simplified circuit design and allowed design automation boosting VLSI progress for more than a decade. Shrinking technology and progressive increase in clock frequency is bringing clock to its crisis. Asynchronous circuits, which are believed to replace globally clocked designs in the future, remain out of the competition due to ...

This paper presents an economic evaluation of gas to liquids (GTL) project using “South-Pars” gas field of Iran based on the latest actual performing GTL projects. Iran has the world’s largest reserves of natural gas and can satisfy the projected long-term market demand of GTL products which have lower pollution and higher quality than refinery products. The results of cost-benefit analysis sho...

Neuronal networks operate over a wide range of activity levels, with both neuronal and nonneuronal cells contributing to the balance of excitation and inhibition. Activity imbalance within neuronal networks underlies many neurological diseases, such as epilepsy. The Caenorhabditis elegans locomotor circuit operates via coordinated activity of cholinergic excitatory and GABAergic inhibitory tran...