Background Chronic hepatitis B virus (HBV) infection is a global health threat for which there an urgent need to develop novel therapeutics. Methods Aurintricarboxylic acid (ATA) has been demonstrated with broad-spectrum antimicrobial and antiviral activities. In this study, we implemented ATA treatment in HBV-infected HBV-transfected hepatocytes uncover whether inhibits HBV replication its und...

Evaluation of miRNA-122, miRNA-149, miRNA-199a, and miRNA- let7 Expression in HIV, HBV, HIV-HBV Co-infected Patients

hepatitis b vaccination is safe and effective, although breakthrough infection occasionally occurs in those who receive the vaccine and hepatitis b immunoglobulin (hbig) prophylaxis. sequence variation in their antigenic regions is one of the most powerful strategies that are used by viruses to escape recognition by b and t cell-mediated immune responses. the aim of this study was to explore th...

abstract background: naturally occurred hepatitis b virus (hbv) with surface mutations in a variety of chronic hepatitis b (chb) patients who have received no vaccine or hbig bearing substitutions in surface protein, have been reported. objectives: current knowledge concerning the prevalence of these naturally occurring surface antigen mutations among iranian carriers is limited. patients and m...

background: the association between hepatitis b virus (hbv) mutations and hepatocarcinogenesis were reported in the literature. preference for g over c in the leading dna strand has been reported to account for the asymmetry in nucleotide (nt) composition. the aim of this study was to analyze the complete genome sequence and compositional asymmetry of hbv in different stages of hepatitis b. met...

BACKGROUND Hepatitis B virus (HBV) has been classified in eight genotypes, from A to H (HBV/A to HBV/H). HBV genotypes were determined in two groups with different risk factors. METHODS Group I consisted of 42 patients with chronic and acute hepatitis and group II with 25 men who have sex with men (MSM). HBV genotypes were determined by DNA sequencing of the S-gene. RESULTS Both groups diff...

Abstract Hepatitis B virus infection is perilous among the five types of Hepatitis, as it remains clinically asymptomatic. The present study draws up-to-date prevalence (HBV) in general population Mardan, Khyber Pakhtunkhwa Pakistan. blood samples from 4803 individuals including 2399 male and 2404 females were investigated. All suspected analyzed for hepatitis surface antigen using Immuno-chrom...

Background: Hepatitis B virus (HBV) and hepatitis C virus (HCV) infections are the main causes of severe liver failure worldwide. This study was conducted to evaluate the incidence rate and trend of these infections over six successive years from 2008 to 2013 in Ilam Province, western Iran. Methods: We studied the registered data of HBV and HCV based on the National Notifiable Diseases Surveil...

Background: Infection with hepatitis B, C, and delta viruses (HBV/HCV/HDV) caused by mother-to-child transmission (MTCT) is still a serious health problem worldwide. Coinfection HBV/HDV or HCV has been shown to accelerate the progression of chronic HBV infection, resulting in higher mortality. Objectives: The aim this study was evaluate prevalence anti-HCV, anti-HDV, anti-HIV antibodies mothers...