background: bleeding events in hemophilic patients with inhibitors are managed by bypassing agents. currently available agents in iran are recombinant activated factor vii (rfviia; aryogen, aryoseven) and feiba (factor eight inhibitor bypassing agent). no standardized and accurate assay is currently available for monitoring the effectiveness of bypassing agents. we suggested that history of the...

background and aims. hemophilic patients are faced with poor oral hygiene due to concerns about their dental care. the present study assessed the knowledge of hemophilic patients about oral hygiene and the effect of oral hygiene instruction in patients referred to iranian hemophilia society. materials and methods. this cross-sectional study was carried out on 30 hemophilic patients randomly sel...

Abstract Background The purpose of this study was to assess the prevalence of major depressive and anxiety disorders in hemophilic and major beta thalassemic patients related to education of their mothers as a family’s agent. Materials and Methods A case-control study was performed on 34 major beta thalassemic patients. For each patient the control group was selected and matched (with age a...

Hemophilic arthropathy is the most common chronic complication in patients with hemophilia. The pathogenesis of hemophilic arthropathy involves the inflammatory processes associated with rheumatoid arthritis (RA). Determining the severity and/or progression of joint damage is crucial when evaluating the effect of treatment modalities. Identifying reliable biomarkers in the peripheral blood of p...

Hepatitis C virus (HCV) infection is often observed in hemophilic patients who received a blood transfusion of clotting factor concentrates before the mid-1980s, and this increases comorbidity and mortality rates. About 80% of HCV-infected patients have chronic HCV infections, and at least 20% develop end-stage liver disease (ESLD). In Korea, anti-HCV positivity in 1999 was reported to be 49.1%...

Total knee arthroplasty is considered as the treatment of choice for those with end stage hemophilic arthropathy.Compared to other patients undergoing TKA, these patients have specific features such as bleeding tendency, youngerage, pre-operative restricted range of motion (ROM), altered anatomy, and increased complications. This narrativereview of literature is going to inves...

Prevention is essential for avoiding the complications of muscle hematomas (pseudotumors, compartment syndromesand peripheral nerve lesions) in hemophilic patients. This is achieved through early diagnosis of muscle hematomasand proper long-term hematological treatment until they have resolved (confirmed by image studies). Ultrasound-guidedpercutaneous drainage could be benefi...

conclusions more than 40% of the hemophilic patients under 20 years of age in the present study had no immunity against hepatitis a, and 23% of hepatitis c patients had not had a hepatitis a co-infection yet. since hepatitis a can show a fulminant course in hepatitis c patients, vaccination against hepatitis a seems necessary in hemophilic patients in the region. background hemophilic patients ...

abstract background the purpose of this study was to assess the prevalence of major depressive and anxiety disorders in hemophilic and major beta thalassemic patients related to education of their mothers as a family’s agent. materials and methods a case-control study was performed on 34 major beta thalassemic patients. for each patient the control group was selected and matched (with age and s...