Foodborne viruses have been recognized as a growing concern to the food industry and serious public health problem. Hepatitis A virus (HAV) is responsible for majority of viral outbreaks origin worldwide, while hepatitis E (HEV) has also gaining prominence foodborne agent in last years, due its zoonotic transmission through consumption uncooked or undercooked infected meat derivatives. However,...

The person-to-person transmission of the hepatitis A virus primarily occurs in enclosed spaces, particularly in the presence of inadequate hygiene conditions and a high proportion of susceptible individuals. Thus, intimate family contact stands out as a risk factor for HAV infection dissemination. The present study aimed to evaluate the occurrence of household HAV transmission. Blood samples we...

Background and Aim: Hepatitis A virus (HAV) is known to cause several extra hepatic complications including acute acalculous cholecystitis (AAC). ACC due HAV in children usually considered an uncommon complication of viral hepatitis with only 7 cases described literature so far children. To retrospectively investigate the Incidence clinical outcomes induced India. Methods: retrospective review ...

Surveillance was conducted for three clinical syndromes (hemorrhagic fever, encephalitis, and hepatitis) in Cambodian children admitted to the National Pediatric Hospital in Phnom Penh from July 1996 through September 1998. Acute- and convalescent-phase sera, and cerebrospinal fluid, when applicable, underwent diagnostic evaluation for infections with Dengue virus (DENV), Japanese encephalitis ...

Background: Viral hepatitis in acute and chronic form remains a major cause of morbidity and mortality in India. Exposure to Hepatitis A Virus (HAV),Hepatitis E virus (HEV),Hepatitis B Virus (HBV) and Hepatitis C Virus infection vary in different parts of country with different socioeconomic groups. The prevalence of HAV, HEV, HBV, and HCV infection among children up to 12 years, adolescents be...

The genome of hepatitis A virus (HAV) was reverse transcribed into cDNA and molecularly cloned. cDNA clones coding for the capsid protein VP1 that carries the major HAV antigen were cloned into the expression vector pUR290 and expressed in Escherichia coli. The recombinant fusion protein reacted in an immunoblot with rabbit anti-HAV serum, suggesting that it possesses HAV antigenicity.

This retrospective study compares the clinical features, laboratory profile and complications of anti HAV IgM positive acute viral hepatitis A in 138 children between 1-15 year (1-5 year: n=31; 5-10 year: n=85; and 10-15 year: n=22). We found that older children presented with HAV (hepatitis A virus) infection with more atypical manifestations (ascites and splenomegaly) and complications.

We describe a case of acute liver failure caused by echovirus 25 (E25) in a previously healthy 2-year-old boy. Initial serological studies were consistent with hepatitis A virus (HAV), with prozone phenomenon. The similarity of E25 to HAV may obscure accurate diagnosis in some cases of hepatitis.