نتایج جستجو برای: hepatoprotective

تعداد نتایج: 4371  

2012
P. Philomina mary P. Sampath kumar S. Stalin

The present study is aimed to evaluate the hepatoprotective effects of leaves and flower extracts of ervatamia coronaria against CCl4 induced hepatic damage. The results indicated that both flower and leaves extract of ervatamia coronaria exhibited significant effect against CCl4 induced hepatic damage. We also observed the restoration of elevated levels liver marker enzymes includes SGOT,SGPT,...

2005
K. L. Mankani V. Krishna B. K. Manjunatha S. M. Vidya S. D. Jagadeesh Singh Y. N. Manohara

Objective: To evaluate the hepatoprotective activity of Pterocarpus marsupium stem bark extracts against carbon tetrachloride (CCl 4 )-induced hepatotoxicity. Materials and methods: Hepatotoxicity was induced in male Wistar rats by intraperitoneal injection of CCl 4 (0.1 ml/kg/day for 10 days). Methanol and aqueous extracts of P. marsupium stem bark were administered to the experimental rats (2...

Journal: :Molecules 2013
Andréia Assunço Soares Anacharis Babeto de Sá-Nakanishi Adelar Bracht Sandra Maria Gomes da Costa Eloá Angélica Koehnlein Cristina Giatti Marques de Souza Rosane Marina Peralta

The particular characteristics of growth and development of mushrooms in nature result in the accumulation of a variety of secondary metabolites such as phenolic compounds, terpenes and steroids and essential cell wall components such as polysaccharides, b-glucans and proteins, several of them with biological activities. The present article outlines and discusses the available information about...

Journal: :iranian journal of pharmaceutical research 0
mansur mirmohammadlu department of pharmacology and toxicology, school of pharmacy, university of medical sciences, zanjan, iran. seyed hojjat hosseini department of basic science, science and research branch, islamic azad university, tehran, iran. mohammad kamalinejad faculty of pharmacy, shaheed beheshti university of medical sciences, tehran p.o. box 14155-6153, iran. majid esmaeili gavgani department of immunology, faculty of medicine, tabriz university of medical sciences, tabriz, iran. maryam noubarani department of pharmacology and toxicology, school of pharmacy, zanjan university of medical sciences, zanjan, iran. mohammadreza eskandari department of pharmacology and toxicology, school of pharmacy, zanjan university of medical sciences, postal code 45139-56184, zanjan, iran.

diabetes mellitus is associated with complications in several different systems of the body, and the incidence of diabetes is rapidly increasing worldwide. the objective of the present study was to evaluate the effect of aqueous extract of cydonia oblonga mill. fruit on lipid profile and some biochemical parameters in streptozotocin-induced diabetic rats. the extract showed anti hyper lipidemic...

Journal: :avicenna journal of phytomedicine 0
heibatollah sadeghi medicinal plants research center, yasuj university of medical sciences, yasuj, iran abdol saleh hosseinzadeh student research committee, yasuj university of medical sciences, yasuj, iran mehdi akbartabar touri social determinants of health research center, yasuj university of medical sciences, yasuj, iran mehdi ghavamzadeh student research committee, yasuj university of medical sciences, yasuj, iran mehrzad jafari barmak cellular and molecular research center,yasuj university of medical sciences, yasuj, iran hossein sadeghi department of pharmacology, faculty of medicine, yasuj university of medical sciences, yasuj, iran

objective: the present study was conducted to investigate the hepatoprotective activity of hydro-ethanolic fruit extract of rosa canina (r. canina) against carbon tetrachloride (ccl4)-induced hepatotoxicity in rats. methods: male wistar albino rats were randomly divided into six groups of 8 animals of each, including control, toxic (ccl4), r. canina 250, 500, and 750 mg/kg + ccl4 and r. canina ...

Journal: :jundishapur journal of natural pharmaceutical products 0
sajedeh mirshahvalad department of biochemistry, babol university of medical sciences, babol, ir iran; cellular and molecular biology research center (cmbrc), health research institute, babol university of medical sciences, babol, ir iran farideh feizi department of anatomical sciences, faculty of medicine, babol university of medical sciences, babol, ir iran aghdas barkhordar department of biochemistry, babol university of medical sciences, babol, ir iran mohammad bahadoram medical student research committee, ahvaz jundishapur university of medical sciences, ahvaz, ir iran; department of pharmacology and toxicology, herbal research center, pharmacy school, ahvaz jundishapur university of medical sciences, ahvaz, ir iran gholamreza houshmand department of pharmacology and toxicology, herbal research center, pharmacy school, ahvaz jundishapur university of medical sciences, ahvaz, ir iran mahdi pouramir department of biochemistry, babol university of medical sciences, babol, ir iran; cellular and molecular biology research center (cmbrc), health research institute, babol university of medical sciences, babol, ir iran; cellular and molecular biology research center (cmbrc), health research institute, babol university of medical sciences, babol, ir iran. tel: +98-1113236591, fax: +98-1112224152

conclusions the results of this study showed that arbutin may protect the liver against ccl4-induced oxidative damage in rats. this hepatoprotective effect might be correlated with the antioxidant and free radical scavenger effects of arbutin. results treatment with ccl4 for 28 d decreased the levels of total protein and albumin and increased the level of bilirubin and lipid peroxidation. arbut...

Journal: :Indian journal of biochemistry & biophysics 2010
Nitin Verma R L Khosa

Zanthoxylum armatum DC (Rutaceae) is extensively used in indigenous system of medicine as a tonic, carminative, stomachic and anthelmintic. In the present study, the hepatoprotective activity of the leaves ethanolic extract of Z. armatum (EEZA) was evaluated in CCl4-induced hepatotoxicity in rats. The extract at a dose of 500 mg/kg registered a significant decrease in the levels of serum glutam...

2014
João Carlos da Silva Dias J. C. Silva Dias

Carrot is a root vegetable with carotenoids, flavonoids, polyacetylenes, vitamins, and minerals, all of which possess numerous nutritional and health benefits. Besides lending truth to the old adage that carrots are good for eyes, carotenoids, polyphenols and vitamins present in carrot act as antioxidants, anticarcinogens, and immunoenhancers. Anti-diabetic, cholesterol and cardiovascular disea...

Journal: :Acta poloniae pharmaceutica 2012
Surendra K Sharma Suman Neeru Vasudeva

The ethanolic extract of the root of Vitis vinifera (Vitaceae) was evaluated for hepatoprotective activity in rats with liver damage induced by carbon tetrachloride. The extract at an oral dose of 200 mg/kg exhibited a significant protective effect by lowering the serum levels of SGPT, SGOT, alkaline phosphatase and total bilirubin. The extract at this dose also increases the level of total pro...

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