The hepatoprotective activity of the ethanolic extract of the rhizomes of Costus speciosus (Koenig) Sm. was studied on carbon tetrachloride treated rats. The extract registered a significant fall in the levels of serum glutamyl oxalacetic acid transaminase (SGOT), serum glutamyl pyruvate transaminase (SGPT), alkaline phosphatase (ALKP), serum bilirubin (SBLN) and liver inflammation supported by...

The hepatoprotective activity of a fraction of the leaf extract of A.indica against carbon tetrachloride : liquid paraffin (1:1) induced liver damage in rats at doses of 100 mg/kg and 200 mg/kg was evaluated. A significant dose dependent hepatoprotective activity was evidenced by lowering of the elevated levels of glutamate oxaloacetate transaminase (GOT), glutamate pyruvate transaminase (GPT),...

Hepatoprotective activity of the ethyl acetate extract of Teucrium polium L. was investigated using rats with CCl4-induced liver damage. Specific biochemical parameters (glutathione peroxidase, superoxide dismutase, reduced glutathione and total antioxidative status) were estimated in blood and in liver homogenate. Lipid peroxidation in CCl4-intoxicated rats was evidenced by a marked increment ...

Present study was carried out to investigate different extracts of Bauhinia purpurea (B.P) for its hepatoprotective activity against CCl4 induced hepatotoxicity. The different parts of Bauhinia purpurea were collected authenticated and were subjected to extraction using solvent alcohol. Healthy wistar albino rats (150-200g) of male sex were used for the in-vivo investigations. Liver damage was ...

Omega-3 polyunsaturated fatty acids are essential fatty acids offering multiple health benefits. They form an integral part of cell membrane and are indispensable for normal metabolism. Fish oil and flaxseed oil are among few dietary sources of these fatty acids. In present investigation, hepatoprotective potential of omega-3 fatty acids in the form of flaxseed oil and fish oil was assessed aga...

The acetone (AEAC) and aqueous extracts (AQEAC) of Adina cordifolia, belonging to the family Rubiaceae, were studied for hepatoprotective activity against Wister rats with liver damage induced by ethanol. It was found that AEAC and AQEAC, at a dose of 500 mg/kg body weight exhibited hepatoprotective effect by lowering the Serum Glutamate Pyruvate Transaminase (SGPT), Serum Glutamate Oxaloacetat...

Aqueous extracts from seeds of Areca catechu L. (Arecaceae) (AC) and nutgalls of Quercus infectoria Oliv. (Fagaceae) (QI) were investigated for their hepatoprotective potential by studying their antioxidant capacity using four different methods, by determining their in vitro anti-inflammatory activity against 5-lipoxygenase, and by evaluating their hepatoprotective potential against liver injur...

The ethanol extract of C. serratum roots and ursolic acid isolated from it were evaluated for hepatoprotective activity against carbon tetrachloride induced toxicity in male Wistar strain rats. The parameters studied were estimation of liver function serum markers such as serum total bilirubin, total protein, alanine transaminase, aspartate transaminase and alkaline phosphatase activities. The ...

Ethanol extract of leaves and flavonoid (isolated from leaves extract) from Tephrosia purpurea were evaluated for hepatoprotective activity in rats by inducing hepatotoxicity with carbon tetrachloride. These fractions were administered orally at a dose of 100 mg/kg/day. Serum level of transaminases, alkaline phosphate, and total bilirubin were used as biochemical markers of hepatotoxicity. Hist...