نتایج جستجو برای: heritability

تعداد نتایج: 10805  

Journal: :Current Biology 2012

Journal: :Current Biology 2012
John F.Y. Brookfield

What in your view is the distinguishing feature of developmental biology with respect to other natural sciences? It is the source of causality, the genome. Developmental biology differs from other sciences, physics, for example, most profoundly because of the organizing role of the primary informational content of the genome. The genomes of animals are the unique products of a billion years of ...

Journal: :iranian journal of public health 0
m saadat m sadeqi dd farhud a bahaoddini

the fact that life styles and personal interests, aggregate within families suggests that shared environment in addition to shared bioligical factors could play a role in determining the phenotypic similarity of idividuals living in the same household. it is a major concern of cardiovascular epidemiologists to know how much of the familial aggregation of blood pressure is attributable to shared...

Journal: :Proceedings of the National Academy of Sciences of the United States of America 2012
Or Zuk Eliana Hechter Shamil R Sunyaev Eric S Lander

Human genetics has been haunted by the mystery of "missing heritability" of common traits. Although studies have discovered >1,200 variants associated with common diseases and traits, these variants typically appear to explain only a minority of the heritability. The proportion of heritability explained by a set of variants is the ratio of (i) the heritability due to these variants (numerator),...

2017
Alexandra J. Mayhew David Meyre

The goal of this review article is to provide a conceptual based summary of how heritability estimates for complex traits such as obesity are determined and to explore the future directions of research in the heritability field. The target audience are researchers who use heritability data rather than those conducting heritability studies. The article provides an introduction to key concepts cr...

Journal: :Genes, Brain and Behavior 2003

Journal: :Current Directions in Psychological Science 2009

2013
George Shirreff Samuel Alizon Anne Cori Huldrych F. Günthard Oliver Laeyendecker Ard van Sighem Daniela Bezemer Christophe Fraser

BACKGROUND AND OBJECTIVES The severity of HIV-1 infection, measured by set-point viral load (SPVL), is highly variable between individuals. Its heritability between infections quantifies the control the pathogen genotype has over disease severity. Heritability estimates vary widely between studies, but differences in methods make comparison difficult. Phylogenetic comparative analysis offers me...

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