نتایج جستجو برای: heterozygosity
تعداد نتایج: 9512 فیلتر نتایج به سال:
I In this study, allelic polymorphism in candidate genes of TLR4 and IL2 involved in the immune system in four Iranian indigenous chickens were examined using PCR-RFLP technique. A total of 200 birds including common, West Azerbaijan, Marandi, Mazandarani indigenous chicken breeds were selected. For detection of mutation in TLR4 (257 bp) and IL2 (600 bp) genes the PCR products were digested b...
Hemoglobin E-Saskatoon (b22-Glu->Lys) was first described by Vella et al. in a Canadian woman of mixed Scotish and Dutch origin and ever since the variant has been found in Greece, Scotland, Spain and Turkey. Hb E-Saskatoon seems to be an innocuous variant but there are not any available data concerning the association of haemoglobin E-Saskatoon with other haemoglobinopathies. Few published dat...
Low levels of heterozygosity can have detrimental effects on life history and growth characteristics of organisms but more subtle effects such as those on trade-offs of expensive tissues and morphological laterality, especially of the brain, have not been explicitly tested. The objective of the current study was to investigate how estimated differences in heterozygosity may potentially affect b...
The fitness consequences of inbreeding and outbreeding have intrigued biologists for a long time. Recently a measure of relatedness of parental haplotypes has been proposed called mean d(2). This measure is based on a stepwise mutational process and therefore is tailored to microsatellite genetic markers. Theoretical work suggests that mean d(2) typically is less suited for measuring fitness co...
the fast-moving variants, and the homozygotes as shown in Figure 1. (Recently I have also detected a case of heterozygosity of transferrin and complement component C3). However, it is always necessary to keep in mind that a1-antitrypsin heterozygosity is not the only cause of a1 zone-splitting. In fact, in one case the additional band was a-fetoprotein (1). In my experience the better way to as...
The endangered perennial plant Annamocarya sinensis (Dode) Leroy is a tertiary relict tree restricted to southeastern China and northern Vietnam. To explore endangerment mechanisms, develop protection strategies, and guide reintroduction efforts for this species, we investigated genetic diversity and population structure by surveying 70 individuals from three distinct populations using 12 polym...
Genetic markers are used for identity testing and paternity analysis depends on knowing the allele frequencies in the population. Minisatellites show allelic variability in the number of repeat units. We have studied the allele frequencies and heterozygosity of two VNTRs (ApoB and D1S80) in Iranian populations. A total of 96 and 82 chromosomes were analyzed by PCR and gel electrophoresis for Ap...
HERE have been several recent studies of the relationship between the heterozygosity of plant material and the magnitude of some quantitative character, usually yield or stability over a range of environments (YERMANOS and ALLARD 1961; FINLAY 1963; ROWE and ANDREW 1964). In each of these studies, single crosses and their derivatives have been used as the experimental material so that estimation...
Several recent studies based on restriction fragment length polymor phism analysis have supported the concept that the accumulation of multiple genetic alterations converts a normal cell to a malignant cell. Activation of oncogenes and/or inactivation of tumor suppressor genes have been observed during tumor progression in colorectal cancer, lung cancer, and breast cancer. To investigate the po...
The DNAs from two independent pancreatic cancers (tumors 1 and 2) in a patient with multiple endocrine neoplasia type 1 were analyzed. No amplification or gross rearrangement of 19 protooncogenes was observed. However, Southern blot analysis using polymorphic DNA probes revealed loss of heterozygosity at loci on chromosome 11p in both tumors. In tumor 1, an extensive region including the HRAS1,...
نمودار تعداد نتایج جستجو در هر سال
با کلیک روی نمودار نتایج را به سال انتشار فیلتر کنید