Background and Purpose: Apoptosis is a protective cellular process that plays an important role in the development and homeostasis of normal tissue as well as disease-causing factors.. The purpose of this study was The effect of high intensity interval training on the expression of Caspase 3 and 9 horseshoe protein genes in male rats. Materials and Methods: In this experimental study 28 male r...

Introdution: Physical training causes functional and morphological changes in myocardium in response to regulatory adaptations same as Phosphatidilinositol-3-kinase (PI3K) changes. Present study aimed to experimentally investigate the effects of endurance and high intensity interval training on PI3K, structure and function of heart. Methods:  24 adultmale rats (weight 221.6 ± 11.4 grams) divid...

Introduction & Objective: Doxorubicin (Dox) is a very effective drug in the treatment of a wide range of cancers. However, in healthy tissues, especially cardiac tissue, it leads to cytotoxic effects. Therefore, the aim of this study was to determine the effect of 8 weeks of High Intensity Interval training and crocin consumption on serum markers of cardiac toxicity due to doxorubicin injection...

Introduction: The aim of this study was investigating the effect of 4 weeks of high intensity interval training with curcumin supplement on the gene expression of collagen I, II and SMAD/3 in the myocardium of male obese rats with type 2 diabetes. Methods: In this experimental study, 35 male diabetic rats were divided in to 5 groups of seven; normal control, diabetic control, curcumin+diabeti...