HIV-infected cells persist for decades in patients administered with antiretroviral therapy (ART). Meanwhile, an alarming surge drug-resistant HIV viruses has been occurring. Addressing these issues, we propose the application of photoimmunotherapy (PIT) against not only Env-expressing but also HIV. Previously, showed that a human anti-gp41 antibody (7B2) conjugated to cationic or anionic photo...

In this work, we calculated the several physico chemical properties containing of solubility (byVCL), lipophilicity (by milinspiration), dipole and quadrupole moments (by Density FunctionalTheory) for 7 AZT analogs, and compared these parameters with inhibition assays of them. It isresulted; cytotoxicity of these drugs is related with their lipophilicity inversely. With using of thisresult, for...