Traumatic brain injury continues to be the major cause of death in individuals under 44 years of age (Chapter 1). In addition to the high degree of mortality, the morbidity associated with survivors of severe head injury imposes significant social and financial costs upon the community. Despite being such a major public health issue, the mechanisms that result in the irreversible tissue damage ...

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INSTRUCTIONS FOR USE This Medical Policy provides assistance in interpreting UnitedHealthcare benefit plans. When deciding coverage, the enrollee specific document must be referenced. The terms of an enrollee's document (e.g., Certificate of Coverage (COC) or Summary Plan Description (SPD) and Medicaid State Contracts) may differ greatly from the standard benefit plans upon which this Medical P...

rhabdomyosarcoma is a common primary childhood malignancy that rarely metastasizes to the breast. we report a patient with a primary sinonasal rhabdomyosarcoma metastasizing to the breast, with no distant spread. we describe the imaging appearance of rhabdomyosarcoma on magnetic resonance imaging (mri), particularly on diffusion-weighted imaging (dwi) and apparent diffusion coefficient (adc) se...

Keywords Focal brain lesions Magnetic Resonance Spectroscopy Neoplastic The ability to differentiate between neoplastic and non-neoplastic focal brain lesions is critical for appropriate management of patient. Due to low specificity of magnetic resonance imaging (MRI) adequate data for differentiating would not be provided. Magnetic resonance spectroscopy (MRS) is one of the newly supplementary...

Amorphous solid dispersions are of great current interest because they can improve the delivery of poorly water-soluble compounds. It has been recently noted that the highly supersaturated solutions generated by dissolution of some ASDs can undergo a phase transition to a colloidal, disordered, drug-rich phase when the concentration exceeds the "amorphous solubility" of the drug. The purpose of...

Nuclear magnetic resonance (NMR) spectroscopy is a principal analytical technique used for the structure elucidation of molecules. This Primer covers different approaches to accelerate data acquisition and increase sensitivity NMR measurements through parallelization, enabled by hardware design and/or pulse sequence development. Starting with hardware-based methods, we discuss coupling multiple...