abtract background: in nuclear medicine, phantoms are mainly used to evaluate the overall performance of the imaging systems and practically there is no phantom exclusively designed for the evaluation of the software performance.  in this study the hoffman brain phantom was used for quantitative evaluation of reconstruction techniques. the phantom is modified to acquire tomographic and planar i...

OBJECTIVE We examined the difference of the effect by data to revise a gamma camera difference. The difference-correction method of the camera is incorporated in eZIS analysis. METHODS We acquired single photon emission computed tomography (SPECT) data from the three-dimensional (3D) Hoffman brain phantom (Hoffman), the three-dimensional brain phantom (3D-Brain), Pool phantom (pool) and from ...

Purpose: In longitudinal oncological and brain PET/CT studies it is important to understand the repeatability of quantitative PET metrics in order to assess change in tracer uptake or binding. The present studies were performed in order to assess the aspects of PET/CT repeatability related to reconstruction settings, analysis methods, scan duration (or image noise) and position in the field of ...

OBJECTIVE We developed a modification of the acquisition zoom technique, referred to as differential magnification (DM), to improve the pixel resolution with fanbeam collimators. This study evaluated the effects of DM on brain SPECT image quality. METHODS SPECT imaging was performed using a triple-head camera with and without DM for a line source in air, Jaszczak and Hoffman phantoms, and 15 ...

PURPOSE In longitudinal oncological and brain PET/CT studies, it is important to understand the repeatability of quantitative PET metrics in order to assess change in tracer uptake. The present studies were performed in order to assess precision as function of PET/CT system, reconstruction protocol, analysis method, scan duration (or image noise), and repositioning in the field of view. METHO...

UNLABELLED We report the extended application of an automated computer technique for three-dimensional spatial registration of SPECT and PET studies. METHODS The technique iteratively reslices a misaligned data set until the sum of the absolute differences (SAD) from a reference data set is minimized. The registration accuracy was assessed in Hoffman brain phantom studies collected with known...

BACKGROUND While fluorodeoxyglucose (FDG) and amyloid PET is valuable for patient management, research, and clinical trial of therapeutics on Alzheimer's disease, the specific details of the PET scanning method including the PET camera model type influence the image quality, which may further affect the interpretation of images and quantitative capabilities. To make multicenter PET data reliabl...

Introduction:  The  purpose  of  this  study  is  to  define  the  optimal  parameters  for  the  tomographic  reconstruction procedure in a routine single photon emission tomography. The Hoffman brain phantom  is modified to evaluate the reconstruction method. The phantom was imaged in a 3 and 2-dimensional  conformation and the results were compared.   Materials  and  Methods:  The  2D  phant...

This work is part of the multi-center Alzheimer's Disease Neuroimaging Initiative (ADNI), a large multi-site study of dementia, including patients having mild cognitive impairment (MCI), probable Alzheimer's disease (AD), as well as healthy elderly controls. A major portion of ADNI involves the use of [(18)F]-fluorodeoxyglucose (FDG) with positron emission tomography (PET). The objective of thi...

introduction:  the  purpose  of  this  study  is  to  define  the  optimal  parameters  for  the  tomographic  reconstruction procedure in a routine single photon emission tomography. the hoffman brain phantom  is modified to evaluate the reconstruction method. the phantom was imaged in a 3 and 2-dimensional  conformation and the results were compared.   materials  and  methods:  the  2d  phant...