background beta-thalassemia is the most common hematology disease in human and leptin is one of the hormone that produce by adiposities cells. the purpose of this study was to investigate the relationship between serum leptin level and thyroid hormones in children with major beta-thalassemia. materials and methods this descriptive-cross sectional study was performed on 90 children aged 6-16 yea...

background: the predictive roles of follicle stimulating hormone (fsh), anti-mullerian hormone (amh) and antral follicle count (afc) as ovarian reserve markers in women with different age groups are not established well. objective: this study compares the value of fsh, amh and afc at the time of     in vitro fertilization (ivf) treatment in different age groups. materials and methods: in this c...

background the physiological link between ghrelin and growth hormone (gh) has not yet been fully clarified. furthermore, the existence of a negative feedback mechanism between growth hormone–insulin-like growth factor (gh–igf)-i axis and ghrelin and the influence of amino acids on ghrelin secretion in children remain matters of debate. objectives to understand the regulation of ghrelin secretio...

difficult diagnosis in endocrinology, gynecology, and reproductive medicine. to help solve this issue, the rotterdam consensus conference proposed to include the ultrasonographic follicle count as a new diagnostic criterion, in addition to hyperandrogenism and oligo-anovulation. unfortunately, its assessment does not offer sufficient reliability worldwide. objective: to explore the possible rol...

background: diabetic men have been claimed to have lower serum free testosterone (ft) concentrations than non-diabetic men. the aim of this study was to investigate if serum ft, luteinizing hormone (lh), and follicle stimulating hormone (fsh) concentrations are different in patients with type 2 diabetes mellitus compared with healthy men and to identify factors associated with low serum testost...

in the religion of islam, fasting is obligatory for healthy adults during ramadan. millions of muslims around the world practice fasting in this holy month which may cause different metabolic and hormonal changes due to the restrictions in regular caloric intake. this article was aimed to review some possible effects of ramadan fasting on the endocrine system which has a great impact on physiol...

conclusions while amh receptor expression was higher in experimental rats, their serum concentrations of amh were decreased. further researches with greater sample sizes and measurement of bioactive forms of hormones are recommended to confirm the findings of this study. background anti-mullerian hormone (amh) levels reflect the number of small antral follicles in ovaries and expression changes...

background: the increase in the rate of infertility in women has prompted the need to search for plants with antifertility potentials. objective: the effect of administration of aqueous extract of cnidoscolous aconitifolius leaves for seven days on reproductive hormones of female wistar rats was investigated. materials and methods: sixty female albino rats were grouped into four (a, b, c and d)...

background: azadirachta indica is a tree with most of the parts having various medicinal values. it is however popular because of its high potencies, as antimalarial and anti-fertility agents, which the locals still exploit. objective: we investigated the effect of the methanol leaf extract on the serum levels of the pituitary-gonad hormones and the histo-morphology of the ovary and uterus of a...

case presentation: this case illustrated the development of secondary and subsequently tertiary hyperparathyroidism in a 66-year-old man with a history of chronic renal failure. the patient was managed surgically by parathyroid autotransplantation and serial explantation. discussion: refractory hypercalcemia due to autonomous parathyroid tissue following parathyroidectomy can be managed with gr...