Abstract Background Frequent and rapid development of myelopathy has been reported in individuals with human T-lymphotropic virus type 1 (HTLV-1) infection following solid organ transplantation. There is no information regarding HTLV-2, a closely related that often infects injection drug users. Methods This study includes retrospective analysis all consecutive transplants performed during the l...

Os vírus linfotrópicos de células T humanas (HTLV) foram os primeiros retrovírus potencialmente oncogênicos a serem descobertos e isolados no mundo. Estima-se que 15 20 milhões pessoas estejam infectadas pelo vírus. Até atualidade, quatro variantes descobertas descritas: HTLV-1, 2, 3 4. Destas, apenas o HTLV-1 2 parecem estar distribuídos globalmente, possuindo relevância clínica epidemiológica...

Abstract Background Human T-lymphotropic virus 1 (HTLV-1) is etiologically associated with the chronic inflammatory neurodegenerative disease HTLV-1-associated myelopathy/tropical spastic paraparesis (HAM/TSP) Annexin A1 (AnxA1) an anti-inflammatory protein proposed neuroprotective and anti-neuroinflammatory functions. We hypothesized that ANXA1 gene expression may be dysregulated in HTLV-1-inf...

Abstract Background The human T-cell lymphotropic virus (HTLV) infects a type of white blood cell called or T-lymphocyte. There are two types HTLV, HTLV-I and HTLV-II, which closely related to C retroviruses. is endemic in the Caribbean, Japan, South America, parts Africa. has been recognized as cause adult leukemia (ATL) HTLV-associated myelopathy/tropical spastic paraparesis (HAM/TSP). HTLV-I...

The aim of the present paper is to formulate two new mathematical models describe co-dynamics severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) and human T-cell lymphotropic virus type-I (HTLV-I) in a host. characterizes interplaying between seven compartments, uninfected ECs, latently SARS-CoV-2-infected actively free SARS-CoV-2 particles, CD4+T cells, HTLV-I-infected cells cells. i...

Abstract Backgrounds Therefore, reports on the risk of HTLV-1-related diseases in organ transplantation have increased recent years, and management HTLV renal remains a challenge. Patients methods We retrospectively analyzed four HTLV-1-positive recipients or donors among 89 cases from 2006 to 2021. Results Among recipients, two patients developed adult T cell leukemia/lymphoma (ATL) derived at...

Background: Retroviruses of human T-lymphotropic viruses (HTLV-1 and HTLV-2) have been demonstrated to be endemic in the north-eastern region of Iran. This study aims to determine HTLV-1 and HTLV-2 prevalence among healthy individuals in Neyshabur City during 2010-2014. Methods: A total of 8054 blood samples were collected from healthy participants in Neyshabur, North-Eastern Iran. The blood sa...

Human T-cell lymphotropic virus type 1 , 2 (HTLV-1, 2) is endemic in Particular Areas of the world in which it is associated with myeloid leukemia.In this study, we described the prevalence of HTLV-1, 2 in myeloid leukemia and Mycobacterium Tuberculosis in Iran. We have worked with tissue and blood samples for 2 years. These were the same samples which were positive for myeloid leukemia, Mycoba...

BACKGROUND The presence and origin of endemic foci of human T-lymphotropic virus type 2 (HTLV2) infection in Africa remain a matter of debate. METHODS To better appreciate such determinants, we performed a survey of 1918 inhabitants from Cameroon forest areas, including 1051 Bakola Pygmies and 867 Bantus. RESULTS The overall HTLV-1/2 seroprevalence was 4% (49 cases of HTLV-1 and 27 cases of...

BACKGROUND Human T lymphotropic virus types 1 (HTLV-1) and 2 (HTLV-2) are frequent copathogens among individuals infected with human immunodeficiency virus type 1 (HIV-1). The long-term effects of coinfection are unknown, and little information exists regarding how levels of HTLV-1/2 viral burden are affected by antiretroviral medications. METHODS Factors associated with HTLV-1/2 viral burden...