background: progressions in science and technology have generated several methods for delaying preterm delivery and abortion; therefore, discovering an easy, non-invasive, practical, and non-expensive predictive factor can help us to perform preventive methods in healthy pregnant women, without any risk factors. objective: to indicate an appropriate index for predicting abortion in early pregna...

the purification of biomolecules is a necessary step in many biochemical researches. in this regard, developments of convenient, specific and low cost methods of purification are of particular interest. given the human hemoglobin (hb) affinity toward some charged carbohydrates, interaction of this molecule with human chorionic gonadotropin (hcg) which is a glycoprotein hormone containing sialic...

placental site trophoblastic tumor (pstt) is the rare variant of gestational trophoblastic diseases (gtd), which differs histologically and immunologically from gtd. diagnosis of pstt is often difficult and delayed. in most cases, diagnosis is not possible until the surgery is performed. the most therapeutic choice is hysterectomy and it is usually successful. here we report two cases of pstt.

a highly sensitive electrochemicalimmunosensor was developed to detect hcg based on immobilization ofhcg-antibody (anti-hcg) onto robust nanocomposite containing gr, chit,1-methyl-3-octyl imidazolium tetra fluoro borate ionic liquid (il)(gr-il-chit). aunps were used to immobilize hcg antibody on the modifiedelectrode. the amine groups of the antibody are covalently attached toaunps/gr-il-chit n...

background and aims: some nanoparticles can be used in immunoassays to increase sensitivity. this study aimed to evaluate a novel nano-immunoassay based on bovine serum albumin nanoparticles (bsa nps). materials and methods: at first, the nanostructure was synthesized, and then applied as a tag in the nano-immunoassay. then the concentration of β-subunit of human chorionic gonadotropin (βhcg) i...

routinely, a bolus of 5.000-10.000 iu human chorionic gonadotropin (hcg) is usedfor the final follicular maturation and ovulation as a standard method. hcg has thesame effect of luteinizing hormone (lh) with long half-life. it has the longlutheotrophic effect which increases the risk of ovarian hyper stimulation syndrome(ohss). recently, gonadotropin-releasing hormone agonist (gnrh-a) trigger h...

many findings point to the presence of a close relationship between the immune, endocrine and neurologic systems. for example the suppressive effects of β-human chorionic gonadotropin (β-hcg) on il-l production, the potentiative effect of enkephalins on lymphocyte functions and the suppressive effect of leuteinizing hormone (lh) on natural killer (nk) cell activities have been clearly establish...

background: gonadotropin-releasing hormone agonists or antagonists are used in assisted reproductive technique cycles as premature luteinizing hormone secretion inhibition. studies have been reported different and contradictory results on the serum progesterone effect on intra-cytoplasmic sperm injection. objective: the purpose of this study was to evaluate the effect of serum progesterone leve...