نتایج جستجو برای: human granulocyte macrophage colony stimulating factor

تعداد نتایج: 2381015  

Journal: :iranian journal of basic medical sciences 0
abbas shirdel internal medicine department, ghaem hospital, mashhad university of medical sciences, mashhad, iran houshang rafatpanah immunology research centre, buali reserch institute, mashhad university of medical sciences, mashhad, iran centre for integrated genomic medical research (cigmr), the university of manchester, manchester, uk hassan rahimi internal medicine department, ghaem hospital, mashhad university of medical sciences, mashhad, iran abdol rahim rezaee immunology research centre, buali reserch institute, mashhad university of medical sciences, mashhad, iran mahmoud reza azarpajooh neurology department, ghaem hospital, mashhad university of medical sciences, mashhad, iran

introduction genetic background has known to be associated with the outcome of human t cell lymphotropic virus (htlv) type i infection. in the present study we investigate the association between gm-csf gene polymorphisms with the outcome of htlv-i infection. materials and methods we analyzed 3 single-nucleotide polymorphisms in the promter region of granulocyte macrophage colony stimulating fa...

Journal: :international journal of reproductive biomedicine 0
behnaz sheikholslami mojdeh salehnia mojtaba rezazadeh

the cytokine of granulocyte macrophage colony stimulating factor (gm-csf) is a glycoprotein, which is synthesized in the female reproductive tract and has embryonic trophic effect in mammals. the objective of this study was to examine the optimal dosage of gm-csf to improve the mouse embryo development in vitro. to collect two and eight cells embryos, the pregnant nmri mice were sacrificed by c...

Journal: :iranian biomedical journal 0
مهریار حبیبی رودکنار mehryar habibi roudkenari سعید بوذری saeid bouzari مانا علومی mana oloomi انیس جعفری anis jafari نادر شاهرخی nader shahrokhi محمدعلی شکرگزار mohammad ali shokrgozar

fusion of two genes at dna level produces a single protein, known as a chimeric protein. immunotoxins are chimeric proteins composed of specific cell targeting and cell killing moieties. bacterial or plant toxins are commonly used as the killing moieties of the chimeric immunotoxins. in this investigation, the catalytic domain of shiga-like toxin (a1) was fused to human granulocyte macrophage c...

Journal: :iranian biomedical journal 0
مهریار حبیبی رودکنار mehryar habibi roudkenar سعید بوذری saeid bouzari yoshikazu kuwahara آمنه محمدی روشنده amaneh mohammadi taisuke baba مانا علومی mana oloomi

background: immunotoxins are comprised of both the cell targeting and the cell killing moieties. we previously established a new immunotoxin, i.e. shiga toxin granulocyte macrophage-colony stimulating factor (stxa1-gm-csf), comprises of catalytic domain of stx, as a killing moiety and gm-csf, as a cell targeting moiety. in this study, the ability of the immunotoxin to induce apoptosis and doubl...

Journal: :Cancer research 1984
K Motoyoshi Y Ishizaka K Ikeda S Kajigaya K Hatake S Shionoya M Saito Y Miura

The effects of bone marrow-conditioned medium obtained from colony-stimulating factor-producing tumor-bearing nude mice (G-BM-CM) on mouse and human granulocyte-macrophage colony formation and mouse erythroid colony and burst formation were studied. Addition of G-BM-CM into the mouse granulocyte-macrophage colony-forming system containing colony-stimulating activity more strongly inhibited gran...

A RABBANI, B GOLIAEI,

The role of alveolar macrophages in the production of granulocyte/ macrophage colony-stimulating factor(s) by the rat lung was investigated. Lavaged lungs, when incubated at proper weight per volume of culture medium, produced the same amount of colony-stimulating factor as unlavaged ones. Both lavaged and unlavaged lungs produced similar types of colony-stimulating factor (s). Prolonged i...

Journal: :medical journal of islamic republic of iran 0
b goliaei from the institute of biochemistry and biophysics, tehran university of medical sciences, tehran, islamic republic of iran. a rabbani

the role of alveolar macrophages in the production of granulocyte/ macrophage colony-stimulating factor(s) by the rat lung was investigated. lavaged lungs, when incubated at proper weight per volume of culture medium, produced the same amount of colony-stimulating factor as unlavaged ones. both lavaged and unlavaged lungs produced similar types of colony-stimulating factor (s). prolonged incuba...

Journal: :Journal of Experimental Medicine 2001

2008
Wassim Mchayleh Rajesh Sehgal James Natale Gurkamal Chatta

Abbreviations: acute myeloid leukemia, (AML); American Society of Clinical Oncology, (ASCO); bone marrow, (BM); end stage renal disease, (ESRD); erythropoietin, (EPO); granulocyte colony-stimulating factor, (G-CSF); Granulocyte-macrophage colony-stimulating factor, (GM-CSF); hematopoietic growth factors, (HGFs); hematopoietic stem cell, (HSC); hemoglobin, (Hgb); idiopathic thrombocytopenic purp...

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