BACKGROUND Xylitol is a 5-carbon sugar that can lower the airway surface salt concentration, thus enhancing innate immunity. We tested the safety and tolerability of aerosolized iso-osmotic xylitol in mice and human volunteers. METHODS This was a prospective cohort study of C57Bl/6 mice in an animal laboratory and healthy human volunteers at the clinical research center of a university hospit...

BACKGROUND Malaria and alcohol consumption both represent major public health problems. Alcohol consumption is rising in developing countries and, as efforts to manage malaria are expanded, understanding the links between malaria and alcohol consumption becomes crucial. Our aim was to ascertain the effect of beer consumption on human attractiveness to malaria mosquitoes in semi field conditions...

INTRODUCTION Homeopathic Pathogenetic Trials (Proving) are human studies to examine the pathogenetic effects of investigational drugs in high dilution on healthy volunteers. As a part new coronavirus nosode development process for prophylactic use, phase 1 study was conducted. The documentation proving symptoms fast-track pandemic condition objectives this study. MATERIALS AND METHODS An open-l...

Volunteers bring support and validation to those who are marginalized in society. Further, volunteers serve as a means of care concern that extends the mission programmatic objectives human service organizations. beneficial However, there critical benefits volunteering make being volunteer worthwhile. The model for this discussion is three areas development: personal development, skills develop...

background: this study was conducted to investigate the influence of toxoplasma gondii infection on spermatic and hormonal parameters in a pilot sample of immunocompe­tent human male subjects. methods: this cross sectional, observational pilot study on 60 immunocompetent hu­man male subjects aged between 18 and 60 yr old was conducted between 2012 -2013. blind evaluation of serological markers ...

the activity of cytochrome p450 isozyme 3a4 (cyp3a4) enzyme and p-glycoprotein (p-gp) is modulated by grapefruit juice and herbal drugs. cyp3a4 is the major phase i drug metabolizing enzyme and p-gp is an atp-dependent drug efflux pump that regulates the intestinal absorption of orally administered drugs. honey is commonly consumed as a dietary supplement. however, its influence on human cyp3a4...