Hypercalciuria is an important, identifiable, and reversible risk factor in stone formation. The foremost and most fundamental step in dissecting the genetics of hypercalciuria is understanding its pathophysiology. Hypercalciuria is a complex trait. This article outlines the various factors that compromise the attempt to dissect the genetics of hypercalciuria, summarizes the clinical and experi...

idiopathic hypercalciuria is a leading cause of frequency-dysuria syndrome in childhood. different modes of inheritance have been suggested in this disease. this article presents the occurrence of idiopathic hypercalciuria in all children of two families. in the first family, a 5.5 year old girl with a history of renal stones and dysuria due to hypercalciuria, had two involved brothers and one ...

An oral calcium loading test was performed on 55 patients with upper urinary tract stones to find absorptive or renal hypercalciuria. The mean urinary calcium excretion level of this patient group was significantly greater than that of a control group of 10 patients without abnormal upper urinary tract. Idiopathic hypercalciuria defined as more than 250 mg per day in males and more than 200 mg ...

The causes for the hypercalciuria and diagnostic criteria for the various forms of hypercalciuria were sought in 56 patients with hypercalcemia or nephrolithiasis (Ca stones), by a careful assessment of parathyroid function and calcium metabolism. A study protocol for the evaluation of hypercalciuria, based on a constant liquid synthetic diet, was developed. In 26 cases of primary hyperparathyr...

Hypercalcemia and hypercalciuria secondary to immobilization can be occasionally severe, producing an array of symptoms. This study looked at possible determinants of hypercalcemia and hypercalciuria in immobilized trauma patients. This is a prospective observational study carried out over a period of 7 months. Fifty-five immobilized trauma patients were evaluated weekly for 4 weeks for symptom...

BACKGROUND Renal malformations including vesico-ureteral reflux (VUR) are associated with urolithiasis. However, studies on urinary calcium excretion in children with VUR have not been reported. This study was conducted to find out whether children with VUR have a higher prevalence of hypercalciuria and whether their family members are affected by hypercalciuria and/or urolithiasis. METHODS W...

Introduction: Urinary tract infection (UTI) is common in children. Recurrent UTI causes serious complications such as renal scarring, proteinuria and hypertension. Recent studies have  reported  that hypercalciuria  may  be considered  a  risk  factor  for  recurrent  UTI. Materials and Methods: In this study 110 children 2months to 13years o...

INTRODUCTION Hypercalciuria may be a sign of over active bladder, these symptoms may be treated if we get rid of hypercalciuria. OBJECTIVES This paper is intended to get to the prevalence of hypercalciuria in girl kids with over active bladder. PATIENTS AND METHODS All patients with index of over active urinary bladder who admitted to Amir-Kabir hospital of Arak and children who have admitt...

Flocks (1939) first noted an association between renal stone disease and increased calcium excretion in the urine, but it was not until 1953 that Albright, Henneman, Benedict & Forbes coined the term ‘idiopathic hypercalciuria’ to describe the disorder, suggested that it might be tubular in origin, and drew attention to the hypophosphataemia which frequently accompanies it. A few years later He...

BACKGROUND Kidney stone formation is a major socioeconomic problem in humans, involving pain, recurrent treatment and renal insufficiency. As most renal precipitates contain calcium as a major component, hypercalciuria is the main risk factor for renal stone formation. Different forms of hypercalciuria can be classified, which primarily arise from defects in the main organs involved in calcium ...